Lifespan (Why We Age. and Why We Don’t Have To)

Very impressive! How extending life may actually be easier than finding a cure for cancer. The future may be sooner than you think!

The book arrived bent and dirty. It seems like it has been used and handled very carelessly

The book that I received is a 2nd hand which is not indicated, the book is dented on its corners and even has a "dog ear"(folded portion that serves as a bookmark) on page 297. Worse is I needed to disinfect it immediately because it has dirty finger prints on the sides.

The subject of extending life is obviously fascinating . The book makes you understand how it will happen . As it will happen. The second part of the book is completely diffident and explains what are the implication of longer life for our societies . What can happen and particularly it compares our future to what has happened in our history. Perfect analysis . Usually these books are either catastrophic , negationist or everything is going to be perfect. Here the author gives a very balanced view . Excellent .

Excellent book and well researched. It had a lot of useful infomation in it from a Harvard professor. The only downside is that iit is very long and in small print so there os a lot of get through to get to the end recommendations

Author talks about himself too much. Very little useful information.

This book is a very comprehensive view of not only the current research in anti-aging, but a sincere consideration of the implications of prolonging average lifespan and health span. Dr. Sinclair makes the science understandable while also bringing personal passion to the issue of aging and long-term health - it really means something for him. The book discusses WHY we age at a biological level, what that means for the pathways in which to stop that biological process, and the current research of what health practices, lifestyles, and most importantly which molecules can prevent or slow the process. After all, our bodies do not simply say "Well, looks like we are 60, time to start shutting down." There must be something happening at a cellular and biological level in our bodies that causes us to be "60" and not "20", so what is it? And given that there must be a process, why should it be impossible to intervene in it? On this premise, Dr. Sinclair discusses how a loss of information and DNA degradation contributes to a loss of cellular function that precipitates aging. He then goes on to explain not just THAT diet and exercise are helpful in increasing health span, but WHY - a much more scientific approach than just saying "eat your grems, they're good for you." Beyond that, and most interestingly, he relates the latest research on naturally-occurring molecules that can reactivate cellular function, and the promise such molecules may have - which to-date have demonstrated little to no negative side-effects and have moved into human trials. Because Sinclair himself is leading much of the research in his Harvard lab, this is not just another health book from another health guru attempting to peddle "advice" for money. It is a true attempt to communicate actual findings from esteemed research laboratories, and an attempt to do so so that the public can understand the latest science themselves instead of waiting for a patented pill to be offered via a doctor's office years from now with only half-baked information. I also want to note that, per his numerous statements in public forums, interviews and the book itself, Dr. Sinclair does not promote or profit from the sale of any commercial product - such as NMN, Resveratrol or NR. Though his name is invoked on many websites to give clout to commercial products, he makes a point to never endorse or sign a deal with any such commercial producer, precisely so that his integrity and the validity of the research cannot be called into question. Any stake that he has in any related company is disclosed and the nature of the involvement discussed, but again, he purposely does not profit from or endorse any commercial product. Personally, I recommend coupling or preceding the book with podcasts on which he has been a guest so that you can get a light, layman's background in the science before delving into the depth of the text itself. While the text is reasonably easy to follow, the information is still weighty and may be benefit from hearing a more high-level version first.

It’s been a good 9 months or there around, since I have a read this book and listened to the author on the Joe Rogan podcast. I thought it was a brilliant book, and even as a 23 year old it has played an influence on my behaviour by changing certain things about my lifestyle. It could be placebo, but I feel since I have changed my behaviours, I have a lot more energy in day to day tasks and generally a lot sharper mentally and physically. I don’t often keep hold of books but this one I have, and will most likely read it again, especially in the future when I’m slightly older and perhaps have a different perspective on life. Whilst the book is scientifically written, it is simply written into layman’s term for the simple folk like me to understand. David makes great connections for both sides of the argument of extending lifespan, including personal conversations he has with his son and his father. The only downfall I’d say is, I struggled at the start of the book and was overwhelmed with understanding cells but as mentioned, it’s put into layman terms and even includes diagrams - I took a short break from the book and listened to the podcast a couple of times and in the end, I feel like this book has improved my understanding of the body better and made me think more about the fuel I put in to me.