Glenmark Therapeutics Esomeprazole Magnesium USP 20mg, Delayed Release Capsules, Treats Frequent Heartburn, 42 Capsules

I have been suffering from esophageal erosion for the past few years. Mine got so bad that anytime I had salty or spicy food my throat would go into a spasm where I couldn't swallow and couldn't throw up either. All I could do was take very small of sips of water until the spasms subsided, but talk about creating a major panic. I had to make sure I ate very slowly and with plenty of water. Fast forward after taking this product for four days, and it's a complete game changer. My reflux was particularly bad after waking up. I'm only four days in, and it's not totally gone, but I would say it's 80% better. I do get a very mild headache when I first take it and it can also cause some gastrointestinal upset--loose or soft stools but not diarrhea. Side effects vary by the individual. Overall, I wish I had taken this years ago instead of needlessly suffering. Good product at an affordable price that's effective.

These work for me better than other brands I have ordered. I wish they would put them all in one bottle. There is no need for 3 when they would fit into one. I would recommend.

Excellent product works just as good as the name brand Nexium

Taking Glenmark caps for 5 months..Esomprazole caps very effective..provide all day relief of heartburn from acid reflux. Excellent price

Fast Relief and Reliable Protection for Frequent Heartburn I’ve tried several options over the years for heartburn, but this Glenmark Therapeutics Esomeprazole Magnesium 20mg has proven to be both effective and reliable. The delayed-release capsules start working within a day, and after a couple of days of consistent use, I noticed my heartburn episodes became much less frequent and far less severe. I appreciate that the 42-capsule pack covers a full two-week treatment course, which makes it easy to stay on schedule. The capsules are small enough to swallow without issue, and I haven’t noticed any odd aftertaste. For me, it’s worked especially well when taken first thing in the morning before breakfast, as directed. One thing to keep in mind is that this isn’t meant for instant relief—you won’t pop one and feel better in 5 minutes. It’s more about building protection over time, and once it’s in your system, it really helps prevent that painful burning from even starting. Also, this product is intended for frequent heartburn (two or more times a week), not the occasional flare-up. Bottom line: A dependable, easy-to-take option for keeping frequent heartburn under control. Works best when used consistently as directed, and it’s been a solid addition to my routine for lasting relief.

[1] Source : This is an FDA-approved, OTC generic proton-pump inhibitor [PPI] made in India by Graviti Pharmaceuticals Private Ltd. (FEI 650884781), and sourced and sold here by the marketing labeller Glenmark Therapeutics Inc. (NJ). [2] Contents : The three-bottle box is an ode to plastic waste -- each unopened bottle of about 55 cc is 3/4 empty. The active ingredient is a magnesium salt in trihydrate form of esomeprazole in a delayed release form. It is the chiral s-isomer of omeprazole, an older PPI; though chemically identical, these isomers do not have identical clinical effects. Clinical trials showed that, at appropriate standard dosages, esomeprazole provides more effective control of intragastric pH in patients with symptoms of gastroesophageal reflux disease [GERD] than omeprazole (as well as the other '-prazole' PPIs). Besides being much cheaper than Nexium, this generic is less expensive than other generic esomeprazole brands (some of which made by the same manufacturer). Two of its listed inactive ingredients, see my figure, are worth of comment. One is the gelatin used for the capsules, whose origin is unspecified. Those who have vegetarian affinities should be aware that, way more often than not, unspecified gelatin derives from animal tissues (cattle, pork, chicken) rather than cellulose. The other one is the synthetic food colorant Blue No. 2, a petroleum product (like the 2025-banned Red 3). The controversial issue of synthetic food colorants posing hyperactivity risk, in particular to those with ADHD, has received peer-reviewed, published scientific support over the last two decades, with several studies indicating a small but significant association between such dyes and children hyperactivity. The most famous is likely the 2007 Southampton study of McCann and others, a UK's clinical trial [ISRCTN4481308], which in 2008 led the EU's Parliament to ask manufacturers to remove several dyes (including FD&C Blue 2) from foods & beverages, or put on the label the warning "may have an adverse effect on activity and attention in children" -- in stark contrast to such a safety measure about a petroleum product lacking any nutritive value at all, is the FDA's 8-to-6 decision in 2011 against requiring the warning. It took 10 more years for the California's Office of Environmental Health Hazards to issue a peer-reviewed report accepting that synthetic food colorants are associated with adverse neurobehavioral outcomes in children. At any rate, adding unneeded and potentially toxic dyes simply to prettify gelatin capsules seems a daft absurdity. [3] Dosage : Clinically, the dosage varies for different patients and for their gastroesophageal conditions. The Mayo Clinic dot-org wwwebsite provides informative descriptions of the dosages; the dose and treatment duration printed in this product's package matches that recommended to manage heartburn rather than GERD. [4] Risks : Taking a higher dose (e.g., 40 mg), or if the PPI is continued well beyond the recommended course of treatment, or both, involves a number of potential side effects. While the common ones are mostly gastrointestinal and minor, a less common side effect is noteworthy. In 2011, the FDA announced the long-term use of PPIs can lead to low magnesium levels in blood (hypomagnesemia); most reports involved omeprazole or esomeprazole. Although relatively rare, this is a serious condition that can be significantly magnified when taking some antihypertensive drugs (most particularly thiazide or loop diuretics combined with beta-blockers, angiotensin receptor blockers, or ACE inhibitors). I always add a magnesium glycinate supplement when taking this or any other PPI. ~~

Great price versus other products that are the same.

Wife uses them. They seem to work just great. No issues or complaints.