

🐕🦺 Elevate your pet’s skin game — vet-approved, science-backed, and irresistibly soothing!
S3 Pyo Shampoo is a 500mL antiseptic and hydrating formula containing 3% chlorhexidine and 0.5% ophytrium, designed to treat bacterial and yeast skin infections in dogs and cats. Recommended by U.S. veterinarians, it cleanses, soothes, and supports the skin barrier without harsh chemicals, delivering visible relief and healthier skin in just one week.





| ASIN | B0949RKDYC |
| ASIN | B0949RKDYC |
| Age Range Description | All Life Stages |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #407 in Pet Supplies ( See Top 100 in Pet Supplies ) #3 in Dog Shampoos |
| Brand Name | Douxo |
| Color | Translucent |
| Customer Reviews | 4.7 4.7 out of 5 stars (6,961) |
| Date First Available | May 6, 2021 |
| Date First Available | May 6, 2021 |
| Directions | Use as recommended by your veterinarian. Wet the fur with cool water from the neck down. Using 1 pump for every 4 lbs, gently massage shampoo onto skin abnormalities to reach the skin. Repeat until entire body is lightly coated with shampoo and leave on for 10 minutes. Rinse thoroughly with cool water. Shampoo amount can be doubled for dogs or cats with long and/or thick fur. |
| Included Components | Shampoo |
| Item Package Dimensions L x W x H | 7.52 x 3.41 x 2.01 inches |
| Item Weight | 16.9 Ounces |
| Item model number | D98420E |
| Item model number | D98420E |
| Liquid Volume | 500 Milliliters |
| Manufacturer | Douxo S3 |
| Manufacturer | Douxo S3 |
| Model Name | PYO |
| Number of Items | 1 |
| Package Dimensions | 7.52 x 3.41 x 2.01 inches; 1.06 Pounds |
| Size | 16.9 oz |
| Special Ingredients | chlorhexidine, ophytrium |
| Specific Uses for Product | anti-fungal-anti-bacterial |
| Target Audience Keyword | Cats, Dogs, dogs |
| Target Species | dog, cat |
| UPC | 850002593433 |
M**G
Great Product, Immediate Relief
Easy and reliable to pump shampoo out, lathered very well on thick double coat, less redness and irritation right out of the shower, pleasant smell - nothing to complain about.
T**S
Amazing Stuff - fixed my dog's skin issues!
My dog had maybe a yeast infection, skin allergies... idk. He had scabs and dandruff all over his back and belly, and lots of discoloration on his belly which came out of nowhere, He was constantly itching and I felt so bad for him ): I decided to look into it and found people with similar issues. So, with recommendations, I found this shampoo, and also switched his dog food to a better one. With the switch of his dog food, I can't say that one or the other fixed his skin, or both was the solution, but either way, his skin and coat has made a DRASTIC change in just one month. I have been washing him every 3-4 days with this shampoo for a month now, scrubbing him very well and leaving it to sit on him for 5-10 mins. He hates baths but it's what we have to do! This stuff smells great, it suds up and has a nice lather, rinses well, and leaves his coat feeling soft and clean! I can't complain at all. Yes it is pricey as heck, but if it works how can I complain. when I was researching on the internet for my dog's specific issues, I saw people with similar issues say their dog had a yeast infection, and when they took their dog to the vet, this is what their vet recommended! This is what made me take the jump on the purchase and I was not disappointed.
H**R
5 Stars - HIGHLY Recommend! Works Amazing for Allergies!
Hands down the best dog shampoo I've ever used.y American Pitbull is allergic to everything,I even had him undergo the prick test with the Dermatologist & he's allergic to 40 out of 46 items tested for. So his skin is always broken out, even while doing the Allergy Immunotherapy injections, I'm averaging every 3rd day on giving him another bath & this shampoo is helping him so much! He will be completely broken out, red bumps & hives all over his body, I'll give him a bath & within a few hours, or by the next morning (since I usually bathe right before bed) his skin has significantly improved, half the bumps will be gone, most of the hives are completely gone & the redness is nonexistent! The smell is really great as well, it's a lighter scent, I don't smell any chemicals or any of the normal medicated smell at all & it's light enough you can smell it on your pup if you're up close, but otherwise it's not noticeable. The formula is decently thick, it's not runny at all, but it suds up so great as well - another huge thing most medicated shampoos don't do! You also only need a small amount, it actually advises how much to use on the bottle depending on how large your dog is, but it's so easy to suds up, that you don't need much at all. I have a 64lbs Pitbull & I only use 2 pumps on his whole back, 1 on each side & 1 pump on each leg & that's about it. So the cost is a bit expensive, but it lasts forever with how little you need & with how well it works, its 100% worth it. The pump works great, it has the locking mechanism when you turn the pump to the side, so you don't have to worry about it leaking, we transport it every weekend to our MIL's house, and I just throw it in the bag, never leaked before, you don't have to worry about it. I can't recommend this shampoo enough or stress how well its been working for our 4 dogs!
T**S
Every dog is different.
With a pitty with severe allergies (white) her breakouts can get out of control. I have found that bathing her with this shampoo only once a week has done wonders - of course, in addition to her Prednisone every other day.... I recommend this shampoo for help with breakouts, itching, and redness. (I also use Rosemary oil for her paws/scarred areas after her bath) Please note that I have been living with a white Pitty whos vet, food, and special items adds up to about $1,000.00 extra a year (in addition to regular doggie costs) but I will also say - not ALL dogs will react to a product the same way another one does. It will Always be trial and error with allergies and pets. Just like adults - ya gotta find what works for them :) Good luck!
A**.
Works wonders for Skin yeast!
My lab stunk!!! And itched non stop. This shampoo is an absolute lifesaver. The yeasty smell is gone and her skin is so much better and hair is growing back. I did so much research looking for a magic pill and that wasn’t the problem. It was her skin. I now bath her underbody 1x a week to keep her skin healthy. This was recommended by a vet.
S**S
Small bottle but works
I have a shihzu mix and with the weather changing she has been licking and scratching a lot. So she developed fungus on her stomach and paws. I decided to look for shampoo to treat it and since I work with dogs this was a safe smart choice. I did what the instructions said and left it mainly on her stomach and paws for 5-10 minutes. It only has been a few days and her stomach has healed drastically. It’s not 100% better but it says to use 2 times a week. The smell is very light and not overpowering which I like and can be layered. But I would layer it with anything that can’t cause more irritation so a light sensitive condition for allergies would be best after this product. For the price of the bottle is ok, I wish it was a little bigger but for it to be an over the counter medicated shampoo and works, anything for my baby. But it’s not an everyday shampoo, use the bottle as needed and if gets worse then see a vet. Not all products works for every animal, if having doubt confirm with vet but for myself I woulds say the product works
D**A
Helped with my dog’s paw yeast infection. Stopped the itching and redness.
M**A
EXCELENTE PRODUCTO, TENGO UNA BEAGLE CON SINDROME DE CUSHING + DERMATITIS ATOPICA, ASÍ QUE ES MUY COMÚN QUE RECAIGA EN SUS PROBLEMAS DE PIEL, CON ESTE SHAMPOO SUS PROBLEMAS HAN DISMINUIDO UN 80%, HE UTILIZADO MÁS DE 15 SHAMPOOS (SIN EXAGERAR) Y ESTE HA SIDO EL QUE MEJOR LE HA FUNCIONADO Y DISMINUIDO SUS BROTES EN LA PIEL, VALE LA PENA CADA PESO INVERTIDO EN ESTE SHAMPOO.
A**A
les deja el pelaje suavecito y limpio
M**N
Exactly as described. Beautiful scent and a little amount goes a long way. Love it.
S**O
This shampoo will make your pet fur so soft and shiny . And the best part is reduce her dander by 75% … she is more calm now .. less scratchy. Since we live in humid so I shower her every 4 - 5 days .
Trustpilot
2 months ago
4 days ago