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🐾 Stay ahead of pests—because your dog deserves the best defense!
Vectra 3D is a fast-acting, monthly topical flea, tick, and mosquito prevention treatment designed for large dogs (56-95 lbs). It kills fleas within 4 hours, offers waterproof protection after 24 hours, and features a non-greasy formula trusted by veterinarians for nearly two decades—all without requiring a prescription.














| ASIN | B071JS3N2K |
| Active Ingredients | Dinotefuran, Permethrin, Pyriproxyfen |
| Age Range Description | 8 Weeks or Older |
| Allergen Information | Abalone Free |
| Best Sellers Rank | #5,704 in Pet Supplies ( See Top 100 in Pet Supplies ) #11 in Dog Flea Pills |
| Brand | VECTRA 3D |
| Brand Name | VECTRA 3D |
| Customer Reviews | 4.4 out of 5 stars 1,329 Reviews |
| Dog Breed Size | Large |
| Global Trade Identification Number | 00851321007106 |
| Included Components | 3 tubes |
| Item Form | Drops |
| Item Type Name | pet-flea-drops |
| Item Volume | 0.48 fluid ounces |
| Item Weight | 1.13 g |
| Manufacturer | Ceva Animal Health |
| Manufacturer Part Number | D73830F |
| Model Number | D73830F |
| Pet Type | Dog |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 851321007106 |
| Unit Count | 3 Count |
| Volume | 0.48 fluid ounces |
K**B
No ticks!
I was struggling with finding a tick preventative that actually worked where I live. Despite using monthly over the counter topicals my dog was still getting ticks and they weren’t dying after biting him. I heard people recommend Vectra 3D and I’ve been using it for a year now on him and he has not picked up a single tick since I made the switch! My dog has very thick fur so it can be really hard to find little ticks on him so this has been a lifesaver with how well it works. The precise applicator is pretty nice as well, the medication stays in place without much wicking up his fur so he doesn’t get very greasy from it. I always give him a bath right after 24 hours because he does seem a bit itchy from it, but his skin has never been red/flakey/bumpy/etc, I think he just doesn’t like the feel of something on his back. Overall I’d say it’s worth the price, especially if you buy it in bulk for the year when it’s on sale.
S**S
No more ticks
I have been using the product and my dogs doesn't have any fleas or ticks anymore. It's easy to apply also.
F**.
Reliable Preventive Treatment
Vectra is easy to apply. My vet suggests doing it in the evening just before your pet settles down for the night, so it can get absorbed into their system before they roll and rub it off somewhere. Ever since using this product, I have not found any ticks on my pup. (I used to find them periodically. ) And since it also repels mosquitos - it’s another deterrent to help avoid heartworm. Been using for 4-5 years during tick season. Better than the collars, because it is absorbed on the pet and adults and children are not touching it after. Also doesn’t break or otherwise fall off. I’ve never experienced a flea problem with my pets, so I can’t speak to Vectra’s efficacy in comparison. Then again, my dog has never had any fleas since starting Vectra either.
B**Z
Good for my sensitive dog
My dog is sensitive and can use this product. She had seizure activity with a popular pill type.
S**Y
Be careful of overcharging.
This product works well, have been using it for years. I purchased 6months set for large dogs in January 2025 for 79.98. NOW AMAZON IS TRYING TO CHARGE $108!! Won’t be buying it again. I found the same product on another reputable site for $76. SHAME ON AMAZON.
A**S
Works great
I’ve tried lots of other products and keep coming back to this one. It does its job.
L**T
The best otc flea treatment I've ever used!
This is by far the best flea control topical treatment for dogs that you don't need a prescription for. I've never had luck with otc flea treatment up until I found this. It was relentless for my giant pit. The cats had a few as well but not the endless infestation like our pitty. The first couple of hours she went kinda nuts because they were running and freaking out but then she got calm and slept soo incredibly good. The next morning they were about 90% gone. I have vacuumed daily as well and emptied the canister after every use. The first couple of days I had a lot of fleas jumping on me. Last night was the 4th night and I spent about 30 mins combing her from front to back only to find about 10 total that were actually moving very slow and almost dead. I combed my cats last night and only found about 5 on all of my cats... I have over 10 cats btw 😁. I don't want to publicly say the exact amount lol. This morning she has zero on her. I have also washed all of her bedding as well as the couch blankets I use to protect my furniture. She goes outside several times a day and that is actually my next area to treat. I'm in complete shock. I got front line to put on my cats but I haven't had to use them fortunately. Most treatments in the past is a very small vile and you only put it in between the shoulder blades. However this product is a larger vile and you start at the neck and apply a line down the back from neck to tail. I'm in utter shock and soooooo relieved. My girl will finally get her skin back to normal and hopefully her patches of missing fur will come back. I can't take her to the vet because I can't physically get her into our truck. She's not leash trained and she doesn't know how to get into a vehicle and unfortunately she's over weight. Not morbidly but she's definitely over weight and she would need a muzzle because I don't know how she would react around strangers poking at her. I give all shots myself.
A**G
Don’t waste your money.
If I could give it 0 stars, I would. I hardly ever do reviews. The few reviews I do are usually more on the more positive side, but this product is absolute trash. I did two treatments - both when recommended. The first time, it didn’t work that well. The second treatment seemed to increase the amount of fleas my poor dog had. I tried to return it, but of course, by the time I allowed a couple days of the second treatment to show if it worked or not, the return window had closed. A complete waste of money. My dog has been miserable, and this wasn’t the solution to his problem.
Trustpilot
2 days ago
2 weeks ago