--- product_id: 9230173 title: "Niacinamide 500mg Prolonged Release, No Flush, 110 Count | Vitamin B-3 Niacinamide 500 mg, Energy Metabolism & Skin Health Support, No-Flush Formula, Prolonged Release, Non-GMO Tablets" brand: "21st century" price: "R329" currency: ZAR in_stock: true reviews_count: 13 category: "21st Century" url: https://www.desertcart.co.za/products/9230173-niacinamide-500mg-prolonged-release-no-flush-110-count-vitamin-b store_origin: ZA region: South Africa --- # 500mg prolonged release Supports energy metabolism Vegan & Non-GMO purity Niacinamide 500mg Prolonged Release, No Flush, 110 Count | Vitamin B-3 Niacinamide 500 mg, Energy Metabolism & Skin Health Support, No-Flush Formula, Prolonged Release, Non-GMO Tablets **Brand:** 21st century **Price:** R329 **Availability:** ✅ In Stock ## Summary > ⏳ Unlock steady energy & glow with no-flush niacinamide — your daily wellness upgrade! ## Quick Answers - **What is this?** Niacinamide 500mg Prolonged Release, No Flush, 110 Count | Vitamin B-3 Niacinamide 500 mg, Energy Metabolism & Skin Health Support, No-Flush Formula, Prolonged Release, Non-GMO Tablets by 21st century - **How much does it cost?** R329 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/9230173-niacinamide-500mg-prolonged-release-no-flush-110-count-vitamin-b) ## Best For - 21st century enthusiasts ## Why This Product - Trusted 21st century brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Energy & Skin Synergy:** Boosts metabolism while supporting skin, nerves, and digestion - • **Slow-Release Powerhouse:** 500mg niacinamide delivers steady vitamin B-3 without the flush - • **Clean & Conscious Formula:** No sugar, salt, yeast, preservatives, artificial flavors or colors—pure wellness - • **Vegan & Gluten-Free Certified:** Perfect for mindful, health-driven lifestyles - • **Trusted Quality, Proven Results:** 30+ years of cGMP manufacturing excellence from 21st Century ## Overview 21st Century Niacinamide 500mg Prolonged Release tablets provide a steady, no-flush source of vitamin B-3 to support energy metabolism, skin health, and nervous system function. Crafted with vegan, gluten-free, and non-GMO ingredients, this clean formula is free from artificial additives and manufactured under strict cGMP standards for purity and potency. Ideal for professionals seeking sustained vitality and radiant skin without compromise. ## Description Vitamin B-3 plays a key role in converting food into energy and helps maintain the normal function of nerves, skin, and the digestive system. Niacinamide is a good source of vitamin B-3 without the flushing effect associated with niacin. Unconditionally guaranteed for purity, freshness and label potency. No added Sugar, Salt, Yeast, Preservatives, Artificial Flavors or Colors. 21st Century Vitamins and Supplements are manufactured in a cGMP facility under the strictest standards for product quality, including potency and purity. 21st Century prides itself on providing you with a great product at the best value. This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Review: time-release Niacinamie + time-release melatonin... Great sleep FINALLY! - So, wow. Fellow strugglers of proper sleep: perhaps you got to here after learning about the "Healthy Sleep Formula" created by Steve Gibson, as I did. If not, and sleep is an issue for you, I highly recommend you google "Healthy sleep formula" to get to the page on grc .com. That guy has a HUGE following. So much so that when he developed his version 2.0 of the sleep formula and recommend a specific brand of Niacinamide, it sold out everywhere. I knew right then that there must be something to this formula of his. Then he popped back with an update stating that this brand was officially recommended after it had been tested out. I would have never thought that Niacinamide (the amide of nicotinic acid (vitamin B3 / niacin)) + melatonin could be such a magic sleep cocktail. And trust me, at this point I have tried a lot of different supplements. I suffer from the kind of insomnia where you can easily go to sleep, but not remain asleep (sleep-maintaining insomnia disorder)... tossing and turning, rarely getting into deep sleep/REM and waking up everyday feeling pretty exhausted. What a waste of time, honestly. I have been on a long road of finding ways to improve this issue through healthy means, trying my best to avoid actual sleeping pills. Things would work for a bit... then no longer be effective and it would be this endless chase for the next sleep fix. But this formula offered me something new: a combination of 2 time-release pills taken together. It addressed my exact needs. And I am here to say, it works. It WORKS LONG-TERM. I have been doing this formula of time-release Nicinamide and time-release melatonin for several weeks now and its amazing the energy I have now. Many days I wake up about 10-15 minutes before my scheduled alarm for work, have much more vivid dreams, have no issue getting out of bed and out the door, actually feel like going to the gym on my lunch break instead of taking a car nap...it's put me on a great healthy schedule overall and feeling top of my game. I actually look forward to bedtime now. If you do Steve's formula, you have to figure out what is best for you. I will state that I am not a sensitive person and typically need higher dosages of things. In my experimenting I have found that 1250mg of Niacinamide + the 1mg melatonin works best for me to sleep through the night without crossing over into groggy-ville. It is one reason why I like this brand being a lower dosage of 500mg, so I can easily up 1/2 and full dosages cutting the pills. It was very much a goldilocks situation... 1 is too little... 2 is too little... 3 IS TOO MUCH IM IN A HAZE... 2.5 is just right :D So thats my story of Niacinamide and how it's solved my sleep-maintaining insomnia. Pretty amazing, I can't fully believe it yet. Just in case you are wondering the breadcrumb trail of how I got here... it went: friend told me about GABA... and combining with taurine to be more effective. I researched GABA and stumbled on a "sleep hacking through biochemistry" blog... read about all these things to help get you into sleep faster and more lasting, and replacing 5-HTP with tryptophan (but it mentioning a high tryptophan diet might not be healthy so being careful not to use constantly)...blah blah read some reviews on the tryptophan I was getting and mentioning Steve Gibson's healthy sleep formula. His 1st generation formula used a handful of all those aforementioned things till he developed the 2nd gen one. Glad I jumped on board after that point! Its cheap and super effective. Review: Recommended and works - Recommended by my skin doctor and it does have skin benefits that I can see since using. ## Features - Niacin (vitamin B-3) plays a role in energy metabolism.* Niacinamide is a good source of vitamin B-3 with a lower flushing effect than that of niacin.* - Prolonged release vitamins slowly release nutrients into the body over an extended period of time. - No added Sugar, Salt, Yeast, Preservatives, Artificial Flavors or Colors. Gluten Free. Suitable for Vegans. Non-GMO. - 21st Century HealthCare manufactures over 500 vitamins and nutritional supplements that are trusted to be 100% safe, contain the purest ingredients and are guaranteed for label potency. - For over 30 years, 21st Century HealthCare has been dedicated to manufacturing only the highest quality vitamins and supplements in Tempe, Arizona. - These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B004SCKMQS | | Age Range Description | Adult | | Allergen Information | Gluten Free | | Best Sellers Rank | #8,110 in Health & Household ( See Top 100 in Health & Household ) #10 in Vitamin B3 (Niacin) Supplements #870 in Sales & Deals | | Brand | 21st Century | | Brand Name | 21st Century | | Color | No Color | | Customer Reviews | 4.6 out of 5 stars 5,499 Reviews | | Diet Type | Vegan | | Dosage Form | Tablet | | Flavor | Unflavored | | Global Trade Identification Number | 00740985225509 | | Item Dimensions | 2 x 3 x 4 inches | | Item Form | Tablet | | Item Highlight | Vitamin B-3 Niacinamide 500 mg, Energy Metabolism & Skin Health Support, No-Flush Formula, Prolonged Release, Non-GMO Tablets | | Item Weight | 5.28 ounces | | Manufacturer | 21st Century Healthcare, Inc. | | Manufacturer Part Number | B00375BOKU | | Model Name | av2023-21st Century-mg prolonged release tablets-5f0674d8 | | Model Number | 22550 | | Number of Items | 1 | | Primary Supplement Type | Vitamin-b | | Product Benefits | Helps convert food into energy and helps maintain skin, digestive and nervous systems | | Special Ingredients | Gluten Free | | Specific Uses For Product | Digestive,Skin,Energy | | UPC | 740985225509 | | Unit Count | 110 Count | ## Product Details - **Brand:** 21st Century - **Diet Type:** Vegan - **Flavor:** Unflavored - **Item Form:** Tablet - **Primary Supplement Type:** Vitamin-b ## Images ![Niacinamide 500mg Prolonged Release, No Flush, 110 Count | Vitamin B-3 Niacinamide 500 mg, Energy Metabolism & Skin Health Support, No-Flush Formula, Prolonged Release, Non-GMO Tablets - Image 1](https://m.media-amazon.com/images/I/718AmBilbvL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: Are they actually made right in Tempe AZ** A: Yeap **Q: What is the size of these tablets?** A: the size of the cathedral door **Q: why there is Niacin and Niacinamide of the B3, what is the difference** A: Niacin has more uses and positive effects but can cause flushing. Niacinamide doesn't have as many positive effects but will not cause flushing. **Q: Why did the manufacturer make these with talc? it says <2%, but if one takes this every day it adds up!** A: I am not sure. I have not purchased this product since adding PEG to the additional ingredients. Search for a manufacturer that makes niacinamide with as little 'bad' ingredients as possible. ## Customer Reviews ### ⭐⭐⭐⭐⭐ time-release Niacinamie + time-release melatonin... Great sleep FINALLY! *by H***R on October 20, 2016* So, wow. Fellow strugglers of proper sleep: perhaps you got to here after learning about the "Healthy Sleep Formula" created by Steve Gibson, as I did. If not, and sleep is an issue for you, I highly recommend you google "Healthy sleep formula" to get to the page on grc .com. That guy has a HUGE following. So much so that when he developed his version 2.0 of the sleep formula and recommend a specific brand of Niacinamide, it sold out everywhere. I knew right then that there must be something to this formula of his. Then he popped back with an update stating that this brand was officially recommended after it had been tested out. I would have never thought that Niacinamide (the amide of nicotinic acid (vitamin B3 / niacin)) + melatonin could be such a magic sleep cocktail. And trust me, at this point I have tried a lot of different supplements. I suffer from the kind of insomnia where you can easily go to sleep, but not remain asleep (sleep-maintaining insomnia disorder)... tossing and turning, rarely getting into deep sleep/REM and waking up everyday feeling pretty exhausted. What a waste of time, honestly. I have been on a long road of finding ways to improve this issue through healthy means, trying my best to avoid actual sleeping pills. Things would work for a bit... then no longer be effective and it would be this endless chase for the next sleep fix. But this formula offered me something new: a combination of 2 time-release pills taken together. It addressed my exact needs. And I am here to say, it works. It WORKS LONG-TERM. I have been doing this formula of time-release Nicinamide and time-release melatonin for several weeks now and its amazing the energy I have now. Many days I wake up about 10-15 minutes before my scheduled alarm for work, have much more vivid dreams, have no issue getting out of bed and out the door, actually feel like going to the gym on my lunch break instead of taking a car nap...it's put me on a great healthy schedule overall and feeling top of my game. I actually look forward to bedtime now. If you do Steve's formula, you have to figure out what is best for you. I will state that I am not a sensitive person and typically need higher dosages of things. In my experimenting I have found that 1250mg of Niacinamide + the 1mg melatonin works best for me to sleep through the night without crossing over into groggy-ville. It is one reason why I like this brand being a lower dosage of 500mg, so I can easily up 1/2 and full dosages cutting the pills. It was very much a goldilocks situation... 1 is too little... 2 is too little... 3 IS TOO MUCH IM IN A HAZE... 2.5 is just right :D So thats my story of Niacinamide and how it's solved my sleep-maintaining insomnia. Pretty amazing, I can't fully believe it yet. Just in case you are wondering the breadcrumb trail of how I got here... it went: friend told me about GABA... and combining with taurine to be more effective. I researched GABA and stumbled on a "sleep hacking through biochemistry" blog... read about all these things to help get you into sleep faster and more lasting, and replacing 5-HTP with tryptophan (but it mentioning a high tryptophan diet might not be healthy so being careful not to use constantly)...blah blah read some reviews on the tryptophan I was getting and mentioning Steve Gibson's healthy sleep formula. His 1st generation formula used a handful of all those aforementioned things till he developed the 2nd gen one. Glad I jumped on board after that point! Its cheap and super effective. ### ⭐⭐⭐⭐⭐ Recommended and works *by P***L on August 6, 2026* Recommended by my skin doctor and it does have skin benefits that I can see since using. ### ⭐⭐⭐⭐⭐ Yay *by T***L on July 21, 2026* Perfect thanks saves so much time on having to run and pick up but usps is scary they leave packages everywhere and anywhere ## Frequently Bought Together - 21st Century Niacinamide 500 mg Prolonged Release Tablets, 110 Count - Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, 150 Softgels, 150 Day Supply --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.za/products/9230173-niacinamide-500mg-prolonged-release-no-flush-110-count-vitamin-b](https://www.desertcart.co.za/products/9230173-niacinamide-500mg-prolonged-release-no-flush-110-count-vitamin-b) --- *Product available on Desertcart South Africa* *Store origin: ZA* *Last updated: 2026-09-09*