--- product_id: 66321844 title: "Regenerate Advanced Serum Monthly Refill boosting serum clinically proven to regenerate tooth enamel 2 x 16ml" brand: "regenerate" price: "R19" currency: ZAR in_stock: false reviews_count: 13 url: https://www.desertcart.co.za/products/66321844-regenerate-advanced-serum-monthly-refill-boosting-serum-clinically-proven-to store_origin: ZA region: South Africa --- # 3 minutes per day, 3 consecutive days monthly 82% enamel mineral regenerated in 3 days NR-5™ patented enamel mineral technology Regenerate Advanced Serum Monthly Refill boosting serum clinically proven to regenerate tooth enamel 2 x 16ml **Brand:** regenerate **Price:** R19 **Availability:** ❌ Out of Stock ## Summary > 🦷 Elevate your smile game—because your enamel deserves a comeback! ## Quick Answers - **What is this?** Regenerate Advanced Serum Monthly Refill boosting serum clinically proven to regenerate tooth enamel 2 x 16ml by regenerate - **How much does it cost?** R19 with free shipping - **Is it available?** Currently out of stock - **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/66321844-regenerate-advanced-serum-monthly-refill-boosting-serum-clinically-proven-to) ## Best For - regenerate enthusiasts ## Why This Product - Trusted regenerate brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Time-Efficient Treatment:** Only 3 minutes a day for 3 days monthly—fits perfectly into your busy schedule. - • **Powerful NR-5™ Technology:** Exclusive patented formula delivers fresh enamel minerals that integrate seamlessly. - • **Boosts Toothpaste Performance:** Enhances REGENERATE Advanced Toothpaste effectiveness by 43% for maximum results. - • **Supports Sensitive & Aging Teeth:** Targets 80% of common enamel-related issues like sensitivity, yellowing, and transparency. - • **Clinically Proven Enamel Regeneration:** Reverses early enamel erosion with 82% mineral restoration in just 3 days. ## Overview REGENERATE Advanced Serum Refill harnesses patented NR-5™ technology to clinically regenerate 82% of tooth enamel mineral in just 3 days. Designed for busy professionals, it requires only 3 minutes of use per day over 3 consecutive days monthly. This serum not only reverses early enamel erosion but also boosts the effectiveness of REGENERATE Advanced Toothpaste by 43%, tackling common enamel problems like sensitivity, yellowing, and transparency. Ideal for those seeking a scientifically backed, time-smart solution to maintain strong, healthy teeth and a confident smile. ## Description Product Description REGENERATE Enamel Science™ is the first oral care regime with NR-5™ technology able to regenerate tooth enamel* with exactly the same mineral it is made of, reversing the early enamel erosion process. Clinically proven. 80% of common tooth problems, such as sensitivity, transparency and yellowing, are caused by enamel erosion. Enamel is the hardest substance in the body protecting the teeth core underneath. Enamel gets eroded day after day, it happens to everyone, at all ages. The main causes of enamel damage include consuming acidic food and drinks such as fruit, fruit juices and soda, and undergoing teeth bleaching and aligner treatments. Once enamel is eroded, it is not possible for the body to restore it. After 9 years of research, the impossible is made possible with REGENERATE™ Enamel Science, powered by the exclusive and patented NR-5™ technology. At each use, active NR-5™ ingredients combine to form a fresh supply of enamel minerals. These wrap and integrate onto teeth helping to regenerate enamel mineral * with exactly the same mineral tooth enamel is made of. Each REGENERATE Enamel Science™ Advanced Enamel Serum kit contains one NR-5™ Advanced Enamel Serum and one Activator Gel – does not contain mouth trays or mixing stick. When combined with the Activator Gel, the NR-5™ Serum unleashes a concentrated boost of the formula, helping to reverse the early enamel erosion process. The REGENERATE™ Advanced Enamel Serum Kit should be used on a monthly basis for 3 consecutive days. It is preferable to apply at night time and not to consume food or drink immediately after use. Suitable to use when undergoing aligner treatments. After only 3 days, REGENERATE™ Advanced Enamel Serum boosts the effectiveness of REGENERATE™ Enamel Science Advanced Toothpaste by 43%** to maximise the power of enamel mineral regeneration and helps you to keep your teeth strong and healthy. 82% of enamel mineral regenerated in 3 days**, clinically proven. *Acts on early invisible stages of enamel erosion. Helps to regenerate enamel by restoring its mineral content and micro hardness with regular use. Clinically proven. **As demonstrated in a 3-day in vitro test measuring enamel microhardness: combined use of Advanced Toothpaste and Boosting Serum vs Advanced Toothpaste only. *** As demonstrated in a 3 day in vitro test measuring enamel micro hardness: Combined use of toothpaste and serum. Ingredients NR-5 Serum: Glycerin, Calcium Silicate, PEG-8, Trisodium Phosphate, Sodium Phosphate, Aqua, PEG-60, Sodium Lauryl Sulfate, Sodium Monofluorophosphate, Aroma, Hydrated Silica, Synthetic Fluorphlogopite, Sodium Saccharin, Polyacrylic Acid, Tin Oxide, Limonene, CI 77891.Activator Gel: Aqua, Glycerin, Cellulose Gum, Sodium Fluoride, Benzyl Alcohol, Ethylhexylglycerin, Phenoxyethanol, CI 42090.Activator Gel contains: Sodium Fluoride (1450 ppm F) Box Contains Each REGENERATE Advanced Enamel Serum refill kit contains one NR-5™ Serum and one Activator Gel. Manufacturer Contact Information Unilever Dept ER Wirral CH63 3JW UK Review: It Works - I bought this on my dentist’s recommendation as I have defective tooth enamel. I am very impressed with its performance. After my first cycle of 3 consecutive nights’ treatment my teeth have lost their translucent look and are now a healthy, more solid white colour (different from the results of tooth whitening). I’m not sure how many treatment cycles are in the pack but I would guess another two. I was a bit annoyed that the full kit with trays is out of stock so I used my tooth whitening trays instead. These aren’t ideal because their nooks and crannies make mixing the serum and activator awkward, so when the kit with trays is back in stock I will buy it. I’m using the toothpaste and mouthwash for maintenance between the monthly treatment cycles. Regenerate is expensive, but so is a lifetime of dental procedures, and if it can help save my teeth it is well worth the money. Review: good but missing trays and spatula - really good it’s almost like a tooth coating,however its missing two of the things shown in the manual,a mixing spatula and strangely the teeth trays both of which you will need to buy…….makes your teeth feel smooth and protected. ## Features - REGENERATE Enamel Science is the first oral care system able to regenerate tooth enamel mineral*, reversing the early enamel erosion process, keeping teeth healthy and strong - Its unique NR-5 ingredients combine to form a fresh supply of tooth enamel minerals which wrap and integrate onto teeth - 80% of common tooth problems such as sensitivity, transparency and yellowing are caused by enamel erosion and acid attacks - Use for 3 minutes, 3 consecutive days a month. 82% of tooth enamel mineral is regenerated after 3 days***, clinically proven - Boost the effectiveness of REGENERATE Advanced Toothpaste by 43%** - For best results, use in combination with REGENERATE Advanced Toothpaste ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B01LA1XSYM | | Benefits | Regenerates | | Best Sellers Rank | 104,262 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 618 in Dental Care Kits | | Brand | Regenerate | | Brand Name | Regenerate | | Customer Reviews | 4.3 out of 5 stars 681 Reviews | | Global Trade Identification Number | 08710908648113 | | Item Form | Gel | | Item Volume | 32 Millilitres | | Item Weight | 80 Grams | | Item form | Gel | | Manufacturer | Unilever | | Manufacturer Contact Information | Unilever Dept ER Wirral CH63 3JW UK | | Manufacturer Part Number | 9195422 | | Material Features | Feuchtigkeit | | Material feature | Feuchtigkeit | | Model Number | 9195422 | | Number of Items | 2 | | Product benefits | Regenerates | | Scent | fresh | | Scent Name | fresh | | Skin Tone | All | | Skin Type | Combination | | Skin type | Combination | | Unit Count | 1 count | ## Product Details - **Brand:** Regenerate - **Item form:** Gel - **Item volume:** 32 Millilitres - **Item weight:** 80 Grams - **Material feature:** Feuchtigkeit - **Number of items:** 2 - **Product benefits:** Regenerates - **Scent:** fresh - **Skin type:** Combination - **Unit count:** 1 Count ## Images ![Regenerate Advanced Serum Monthly Refill boosting serum clinically proven to regenerate tooth enamel 2 x 16ml - Image 1](https://m.media-amazon.com/images/I/71g83kVTRBL.jpg) ![Regenerate Advanced Serum Monthly Refill boosting serum clinically proven to regenerate tooth enamel 2 x 16ml - Image 2](https://m.media-amazon.com/images/I/71KWv2UbqML.jpg) ![Regenerate Advanced Serum Monthly Refill boosting serum clinically proven to regenerate tooth enamel 2 x 16ml - Image 3](https://m.media-amazon.com/images/I/71Nm54PumVL.jpg) ## Questions & Answers **Q: Hi does this work helping the worn enamel if anybody has used this and has it worked?** A: Yes my sister and myself use it **Q: Can you use this product if you have caps in between your normal teeth.. thanks** A: I don’t know the answer but it should bevon the leaflet inside the bix **Q: Does it heal gums** A: Just teeth. Doesn't do gums any harm though. **Q: Will this work to cover problem discoloured teeth** A: I noticed no real difference and have since returned to standard toothpaste ## Customer Reviews ### ⭐⭐⭐⭐⭐ It Works *by M***N on 26 November 2025* I bought this on my dentist’s recommendation as I have defective tooth enamel. I am very impressed with its performance. After my first cycle of 3 consecutive nights’ treatment my teeth have lost their translucent look and are now a healthy, more solid white colour (different from the results of tooth whitening). I’m not sure how many treatment cycles are in the pack but I would guess another two. I was a bit annoyed that the full kit with trays is out of stock so I used my tooth whitening trays instead. These aren’t ideal because their nooks and crannies make mixing the serum and activator awkward, so when the kit with trays is back in stock I will buy it. I’m using the toothpaste and mouthwash for maintenance between the monthly treatment cycles. Regenerate is expensive, but so is a lifetime of dental procedures, and if it can help save my teeth it is well worth the money. ### ⭐⭐⭐⭐⭐ good but missing trays and spatula *by V***A on 16 April 2026* really good it’s almost like a tooth coating,however its missing two of the things shown in the manual,a mixing spatula and strangely the teeth trays both of which you will need to buy…….makes your teeth feel smooth and protected. ### ⭐⭐⭐⭐ Need to use longer *by S***E on 17 April 2026* Seams good so far always difficult to get. --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.za/products/66321844-regenerate-advanced-serum-monthly-refill-boosting-serum-clinically-proven-to](https://www.desertcart.co.za/products/66321844-regenerate-advanced-serum-monthly-refill-boosting-serum-clinically-proven-to) --- *Product available on Desertcart South Africa* *Store origin: ZA* *Last updated: 2026-07-10*