---
product_id: 645433719
title: "– NAD+ Supplement Precursor, Pure Vitamin B3 Metabolite 2X Double Dose - 1-MNA PRO, NMN & NMNH Alternative NAD Supplement, High Strength Next-Generation, Anti Ageing, Longevity, 30 Capsules"
brand: "endotelio"
price: "R2748"
currency: ZAR
in_stock: true
reviews_count: 13
category: "Endotelio"
url: https://www.desertcart.co.za/products/645433719-nad-supplement-precursor-pure-vitamin-b3-metabolite-2x-double-dose
store_origin: ZA
region: South Africa
---

# Clinically proven energy boost Pure, clean-label vegan formula 2X 1-MNA per capsule – NAD+ Supplement Precursor, Pure Vitamin B3 Metabolite 2X Double Dose - 1-MNA PRO, NMN & NMNH Alternative NAD Supplement, High Strength Next-Generation, Anti Ageing, Longevity, 30 Capsules

**Brand:** endotelio
**Price:** R2748
**Availability:** ✅ In Stock

## Summary

> ⚡ Double the dose, double the edge — fuel your longevity and energy like a pro!

## Quick Answers

- **What is this?** – NAD+ Supplement Precursor, Pure Vitamin B3 Metabolite 2X Double Dose - 1-MNA PRO, NMN & NMNH Alternative NAD Supplement, High Strength Next-Generation, Anti Ageing, Longevity, 30 Capsules by endotelio
- **How much does it cost?** R2748 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/645433719-nad-supplement-precursor-pure-vitamin-b3-metabolite-2x-double-dose)

## Best For

- endotelio enthusiasts

## Why This Product

- Trusted endotelio brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Double Dose Power:** Twice the 1-MNA of standard formulas in a single capsule—equivalent to 2 kg of wakame algae or green tea leaves.
- • **Purest 1-MNA Formula:** No fillers, no additives, EFSA Novel Food approved, GMP-certified EU manufacturing for uncompromised quality.
- • **Effortless Daily Boost:** One capsule a day delivers maximum impact—no stacking, no measuring, perfect for busy professionals and biohackers.
- • **Supports Cellular Longevity:** Activates SIRT1, the key enzyme linked to cellular stress resistance and anti-aging, helping you stay youthful and vital.
- • **Clinically Proven Energy & Anti-Fatigue:** Backed by randomized controlled trials showing improved exercise capacity and reduced fatigue for high-demand lifestyles.

## Overview

Endotelio 1-MNA PRO is a next-generation NAD+ precursor supplement delivering double the pure 1-MNA per capsule, clinically proven to enhance energy and reduce fatigue. Manufactured in a GMP-certified EU facility with clean-label, vegan ingredients, it supports cellular health and longevity by activating the SIRT1 enzyme. Ideal for professionals, athletes, and biohackers seeking a potent, convenient anti-aging and vitality boost.

## Description

Product Description

Review: Enhance Your Daily Life: Purchase 1-MNA for Focus and Rest - I've been taking 1-MNA for the last month, and while there are no life-changing notices, I have noticed increased focus and improved sleep quality. My ability to concentrate on tasks has significantly enhanced, allowing me to be more productive throughout the day. Additionally, I've been falling asleep faster and experiencing deeper, more restful sleep, which has left me feeling more refreshed in the mornings. I'm curious to see if these benefits continue over time and if there are any other effects I might experience as I continue with this supplement. Overall, I'm optimistic about the potential long-term benefits.
Review: Quick direct service - Great

## Features

- DOUBLE DOSE — TWICE THE 1-MNA OF THE BASE FORMULA: Endotelio 1-MNA PRO delivers twice the 1-MNA per capsule compared to the standard Endotelio formula. One capsule equals the 1-MNA equivalent of 2 kg of wakame algae or 2 kg of green tea leaves. For those who want a more intensive daily intake of this Vitamin B3 metabolite — without taking multiple capsules — PRO is the direct answer. Pure formula, no unnecessary additions, maximum 1-MNA.
- ADVANCED ENERGY SUPPORT & ANTI-FATIGUE — AT DOUBLE STRENGTH: More 1-MNA means more support for your body's NAD levels — the molecule your cells rely on for energy production. Clinically studied in a randomised controlled trial showing significant improvements in exercise capacity and fatigue reduction. PRO is built for people who demand more from their supplement: athletes, biohackers, and those with demanding lifestyles who can't afford to run low
- THE PUREST 1-MNA FORMULA AVAILABLE — BACKED BY 100+ STUDIES: No extras. No fillers. No compromises. Just pure 1-MNA at double strength — the molecule at the frontier of NAD research and longevity science. Over 100 peer-reviewed publications. Scientists from 15+ independent research institutes across 4 continents. EFSA Novel Food Approved. GMP-certified EU manufacturing. If you've done your research and know exactly what you want, PRO delivers it.
- EFSA NOVEL FOOD APPROVED · GMP-CERTIFIED EU MANUFACTURING · CLEAN LABEL: Endotelio 1-MNA PRO is one of the only high-strength NAD supplements with full EFSA Novel Food approval for its active ingredient. Manufactured in a GMP-certified European facility. No titanium dioxide (E171), no artificial dyes, no starch fillers. Transparent capsules. Vegan, gluten-free, non-GMO, soy-free, no preservatives, no milk proteins. One capsule per day.
- ONE CAPSULE. DOUBLE STRENGTH. MAXIMUM IMPACT — 30-DAY SUPPLY: No stacking. No measuring. No multiple capsules. PRO packs twice the 1-MNA into a single daily capsule — the most efficient way to get a high-dose 1-MNA intake without complicating your routine. Ideal for those who've tried the Base formula and are ready to step up, or for biohackers who want to start at full strength from day one.
- SIRT1 ACTIVATOR - 1-MNA can complement a diet that supports the production of SIRT1. This is one of the seven enzymatic proteins – sirtuins - that play a significant role in cellular metabolism and the cell's response to stress conditions. SIRT1 is mainly located in the cell nucleus and performs several key functions. The most important is to support the cell's resistance to stress, its ability to survive and the process of differentiation. In young and healthy cells, the level of SIRT1 is high, which allows for better regeneration. A decrease in SIRT1 activity is therefore one of the possible signs of aging. Supporting its production may have a positive impact on our health and vitality.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0D5B6N9RK |
| Age Range Description | Adult |
| Allergen Information | Contains: Gluten Free, Lactose Free, Soy Free |
| Benefits | Anti-Aging, Brain Health Support, Energy Management, Heart Health Support, Immune Support, Metabolism Management |
| Best Sellers Rank | 43,354 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 51 in Vitamin B3 |
| Brand | ENDOTELIO |
| Brand Name | ENDOTELIO |
| Country Of Origin | Poland |
| Customer Reviews | 4.0 out of 5 stars 118 Reviews |
| Dosage Form | Capsule |
| Flavour | Unflavoured |
| Item Dimensions | 50 x 55 x 95 millimetres |
| Item Form | Capsule |
| Item Weight | 1 Kilograms |
| Item form | Capsule |
| Item weight | 1 Kilograms |
| Manufacturer | PHARMENA |
| Manufacturer Part Number | PRO |
| Material Features | GMO Free, Gluten Free |
| Material Type Free | Caffeine Free, Gluten Free, No Artificial Colors, No Artificial Flavors, Soy Free |
| Number of Items | 30 |
| Primary Supplement Type | Vitamin B3 |
| Primary supplement type | Vitamin B3 |
| Special Ingredients | Non-GMO, soy-free, gluten free, no-artificial flavorings, no preservatives, no milk proteins and for vegan |
| Specific Uses For Product | Brain, Heart, Muscle |
| Unit Count | 30 count |
| Unit count | 30 count |

## Product Details

- **Age range (description):** Adult
- **Brand:** ENDOTELIO
- **Flavour:** Unflavoured
- **Item dimensions L x W x H:** 50 x 55 x 95 millimetres
- **Item form:** Capsule
- **Item weight:** 1 Kilograms
- **Primary supplement type:** Vitamin B3
- **Unit count:** 30 Count

## Images

![– NAD+ Supplement Precursor, Pure Vitamin B3 Metabolite 2X Double Dose - 1-MNA PRO, NMN & NMNH Alternative NAD Supplement, High Strength Next-Generation, Anti Ageing, Longevity, 30 Capsules - Image 1](https://m.media-amazon.com/images/I/61GQOkTEcSL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Enhance Your Daily Life: Purchase 1-MNA for Focus and Rest
*by K***. on 4 May 2025*

I've been taking 1-MNA for the last month, and while there are no life-changing notices, I have noticed increased focus and improved sleep quality. My ability to concentrate on tasks has significantly enhanced, allowing me to be more productive throughout the day. Additionally, I've been falling asleep faster and experiencing deeper, more restful sleep, which has left me feeling more refreshed in the mornings. I'm curious to see if these benefits continue over time and if there are any other effects I might experience as I continue with this supplement. Overall, I'm optimistic about the potential long-term benefits.

### ⭐⭐⭐⭐⭐ Quick direct service
*by L***H on 12 April 2025*

Great

### ⭐⭐⭐⭐⭐ A Promising Supplement for Boosting NAD+ Levels
*by S***E on 20 August 2024*

As someone who's always on the lookout for ways to support my overall health, I recently came across Endotelio 1-MNA PRO, a biohacking supplement that claims to help optimize NAD+ levels. I decided to give it a try, and here's my take on it. The product claims to have a "double dose for faster effects," which is always appealing when you're looking for quick results. The fact that it's scientifically formulated and supports cellular health is also a plus in my book. The 30 easy-to-swallow capsules are a convenient size, which is a nice touch. I've been taking the supplement for a few weeks now, and I can say that I've noticed a slight increase in my energy levels and overall well-being. It's hard to say for sure if it's directly attributable to the supplement, but I'm cautiously optimistic about the effects. One thing I appreciate about Endotelio 1-MNA PRO is that it's transparent about its ingredients and formulation. The label clearly lists the active components, which is reassuring. Overall, I'd say this is a promising supplement for those looking to optimize their NAD+ levels and support their cellular health. While the results may vary from person to person, it's worth a try if you're interested in exploring biohacking and anti-aging solutions. Just be sure to consult with your healthcare provider before starting any new supplement regimen.

## Frequently Bought Together

- Endotelio 1-MNA PRO, Anti Aging, Optimizing NAD+, Double Dose for Faster Effects, Biohacking Supplement, Support for Cellular Health, Scientifically Formulated, 30 Easy Swallow Caps
- Charava NAD+ 500mg - 30 Capsules - Enhanced Absorption - NAD+ Booster - Longevity Supplements - Nicotinamide Adenine - 30 Day Supply

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*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-08-14*