---
product_id: 621913111
title: "Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 1.01 fl.oz"
brand: "medicube"
price: "R848"
currency: ZAR
in_stock: true
reviews_count: 13
category: "Medicube"
url: https://www.desertcart.co.za/products/621913111-exosome-shot-zero-7-500-ppm-spicule-facial-serum-liquid
store_origin: ZA
region: South Africa
---

# AHA+BHA+PHA exfoliation blend 15M patented Exosome shots 242% enhanced absorption Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 1.01 fl.oz

**Brand:** medicube
**Price:** R848
**Availability:** ✅ In Stock

## Summary

> ✨ Unlock your skin’s glow with science-backed precision 💉

## Quick Answers

- **What is this?** Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 1.01 fl.oz by medicube
- **How much does it cost?** R848 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/621913111-exosome-shot-zero-7-500-ppm-spicule-facial-serum-liquid)

## Best For

- medicube enthusiasts

## Why This Product

- Trusted medicube brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Next-Level Absorption Boost:** Formulated to increase active ingredient uptake by 242%, ensuring deeper hydration and enhanced skin barrier support.
- • **Seamless Routine Integration:** Effortlessly pairs with Medicube’s booster devices and collagen jelly cream for a professional-grade skincare ritual at home.
- • **Clinically Validated & Gentle:** Non-comedogenic, gluten-free, and low-irritation formula suitable for all skin types, including sensitive skin.
- • **Triple-Acid Exfoliation Power:** AHA, BHA, and PHA work synergistically to refine skin texture, clear dead skin cells, and minimize pores without irritation.
- • **Precision Micro-Needling Effect:** 15 million patented Exosome spicules deliver active ingredients directly into pores for targeted skin transformation.

## Overview

Medicube Exosome Shot Zero 7,500 PPM is a cutting-edge Korean liquid skin booster serum featuring 15 million patented Exosome-coated spicules that deliver active ingredients deep into pores. Enhanced with a potent AHA+BHA+PHA exfoliation complex and clinically proven to boost absorption by 242%, this lightweight, non-irritating serum refines skin texture, tightens pores, and hydrates intensely. Ideal for all skin types, it integrates seamlessly into advanced skincare routines, delivering professional results without needles or downtime.

## Description

Buy medicube Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skincare, 1.01 fl.oz on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Timeless beauty in a bottle - I purchased this product and it waz shipped out and delivered on time and with care. I used it right away and I want to give a detailed description about this item I received. I washed my face and I put a good amount on my face and it felt cool on the skin and right away you can feel it working. Rubbing it on the skin feels pretty good and than you start to feel a prickly feeling the more you work it into the skin, it doesn't hurt, it just feels like if you got fiberglass on the skin and you only feel that when touching the skin otherwise you wouldn't feel anything. A lil time went by and my skin started to get a slight sunburn look, it's exactly the same feeling as when you use dermaroller or stamp. It really is a needle less product and does the very same thing. Skin will feel warm cause blood is coming up to the skin which you want, to receive younger looking skin. It's plumping and the pores shrink and skin really looks amazing as it's working. The prickly feeling lasts throughout the night till next day and you wake up with a glow which feels good cause that's what we're looking for being age 53. I also added the medicube jelly collagen cream to give it an extra boost of hydration and adding the collagen it helps getting directly into the skin and the 2 together work wonders! This product helps us to deliver other products deeper into the skin so using the 2 is like a powerful regimen together! You will love the results. I used red light therapy to help as well and the 3 together makes the skin look amazing as well! It seems the more you touch your skin, the more you're allowing the product to work actively. Think of it as dermarolling and adding in serum as well as the red light therapy only the dermaroller has needles. I've used many products throughout time and dermaroller has given me the best results and these products here give exactly the same results only i love the outcome much better! I will continue using these products and highly recommend them to everyone who truly wants to get their glow back and look years younger in such a short time. My only regret is waiting to purchase these products but now I have them and plan on purchasing more. The night time mask is next. I compare this to frownies but much better due to me not ripping the patches from the skin and the mask is less invasive and works exactly the same, you're not missing any part of the skin when be able to apply it all over the face. I can't wait till I can update this after a couple of months of using these products. I had to explain in detail due to comments I've seen about how much it hurt cause it was the reason it took me longer to purchase this. It doesn't hurt and I hope you purchase it and try it cause I know you won't regret it at all. You'll be smiling cause as we age, our bodies change and I know I lost the natural glow i used to have and it's all back thanks to these products!! Thank you medicube for amazing products!! You have a lifetime customer here and with my skin only getting younger, I hope I can be someone that can help others to achieve the look we're all looking for at this age. I have and id love to see others look in the mirror and say wow! I like who I'm looking at😉
Review: 7500 & No pain, love this light serum, doesn’t pill and I used shot mode first & booster mode with - This is a great serum, I was kind of afraid of trying it at first since I bought the higher level version at 7500 and reading reviews saying that it hurt to put on but once I did try it I was very happily surprised. My skin had a glow to it after application and there was no pain when applying. I rubbed it on my face, cheek to check then forehead then patted it on my face to absorb better and it was more like a very light tingly feeling but only when I patted the spot I was applying the serum to. This isn’t sticky on my skin, there isn’t a scent to it and it’s not painful, it’s also very light weight and comes out of the pump looking like a thin see though gel looking serum so this is one I use first before my pdrn collagen serum or any of my other Medicube serums because this EXO serum seems to be the lightest and very helpful to your skin and pores. This 7500 EXO feels very hydrating as well, I put it on and took a nap and when I woke it felt like a moisturizer on my face but didn’t rub of onto my pillows as it went into my skin, I touched my face and could still feel the very light tingle ( I can’t think of a different name then tingle but it’s more like when you pat or rub it into your face you can feel a light sensation on you face, it’s quite pleasant though.) I am so glad I didn’t purchase the 2000 version because the 7500 it just perfect. You can feel it’s on your face but no pain, I also made sure to use the booster pro age-r on shot mode and used the pore toner pads before. I have sensitive skin and this didn’t bother my face but if you have extremely sensitive skin then maybe try the 2000 first. It really depends on your skin. Personally I wouldn’t waste on the 2000 and just buy the 7500 because it is so light feeling even though you can still feel it, it kinda feels nice when applying. This doesn’t pill on your face if you want to use the booster mode after or apply another serum over it. I used the salmon pdrn serum on booster mode after I waited about 30 minutes for the pore shot serum to dry, I then used the booster mode after for the pore shot by putting it on level 2 and moving it up towards my forehead and still no pain,. Then used the salmon pdrn serum ( highly recommend! ) over it, finishing the 5 min for booster mode and had a lovely glow with pink cheeks. I wish I tried this exosome spicule shot a long time ago, it’s lovely and not painful but you can feel and tell it’s working on your face. I finished with the cooling jelly moisturizer and a collagen liquid mask once the 2 ( patted on my face by hand ) layers of moisturizer had dried. The next day my face felt and looked great with a nice glow to it and a glasssy finish which I absolutely love about the Medicube products, they due all work and makes your face look younger, also helps get rid of fine lines. This serum is an amazing product to start with after applying the toner pad and if you have a shot mode appliance by Medicube make sure to due that first ( before toner ) because it opens your pores and helps the serum penetrate deeper as does the booster mode, it helps your products go deeper into your skin and also helps the serums dry faster as they penetrate your skin deeper, saves time when you’re doing your night routine and is now a staple for me each night. Great skincare products! I love Medicube products and they actually work as well at a great price point compared to other brands. I always update my reviews if something changes, so if my opinion changes about this product I will be updating. For now I can’t wait to try the salmon pdrn EXO shot next!

## Features

- Viral product beloved by everyone - Transform your skin with the Exosome + Shot Booster. Featuring a micro-sized, needle-shaped design and enriched with 15M patented Exosome shots for precise treatment, this booster delivers active ingredients directly to your pores to tackle various skin issues.
- Exosome-Coated Technology - Harness the next-generation skincare with Exosome-coated Spicule and Exosome, penetrating deep into the skin to deliver active ingredients effectively. Our advanced formula is designed to address a range of skin concerns, from pore care to enhancing skin vitality and energy.
- Superior Absorption & Hydration - Achieve unmatched hydration and absorption rates with our formula, which enhances active ingredient uptake by 242% compared to standalone use. Ingredients like Niacinamide and Panthenol boost skin barrier and improve hydration levels, ensuring your skin remains supple and radiant.
- Clinically Proven & Gentle on Skin - Enjoy peace of mind with our clinically validated Tingling Ampoule that is non-comedogenic, tested to be low-irritating, gluten-free, and free from artificial colors. Suitable for all skin types, including sensitive skin.
- Easy to Integrate into Skincare Routine - Apply our Tingling Ampoule easily with a three-step routine, starting with a cleansing pad, followed by the Zero One Day Exosome Shot, and finish with a water-based moisturizer like Medicube’s Collagen Jelly Cream. For an added boost, use after the "Air Shot Mode" of the AGE-R Booster Pro to maximize effects.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0D137TMRB |
| Best Sellers Rank | #352 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #18 in Facial Serums |
| Brand | medicube |
| Brand Name | medicube |
| Customer Reviews | 4.6 out of 5 stars 5,437 Reviews |
| Item Form | Ampoule |
| Item Volume | 30 ml |
| Item Weight | 75 g |
| Manufacturer | Medicube |
| Manufacturer Part Number | PMEKR14040 |
| Model Number | 8809982768524 |
| Number of Items | 1 |
| Product Benefits | Pore Treatment |
| Recommended Uses For Product | Pore Care,Exfoliation,Improving Skin Texture |
| Scent | Aloe |
| Scent Name | Aloe |
| Skin Tone | All |
| Skin Type | Acne Prone, All, Combination, Dry, Sensitive |
| Special Ingredients | Alpha Hydroxy, Collagen, Minerals |
| Target Use Body Part | Face |
| Unit Count | 1.01 Fluid Ounces |
| Use for | Face |

## Product Details

- **Product Benefits:** Pore Treatment
- **Scent:** Aloe
- **Skin Type:** Acne Prone, All, Combination, Dry, Sensitive
- **Special Ingredients:** Alpha Hydroxy, Collagen, Minerals
- **Use for:** Face

## Images

![Exosome Shot Zero 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum with Exosome, AHA+BHA+PHA - Pore Care, Dead Skin Cells, Skin Texture, Korean Skincare, 1.01 fl.oz - Image 1](https://m.media-amazon.com/images/I/71I6MkG0fyL.jpg)

## Available Options

This product comes in different **Pattern, Size** options.

## Questions & Answers

**Q: What are exosomes?**
A: Exosomes are tiny particles, similar to miniature bubbles, that are naturally produced by almost all types of cells. They are much smaller than cells and can carry a variety of important materials such as proteins, fats, and genetic information

**Q: What is the source and function of the Lacto Exosome in Zero Exosome Shot?**
A: The Lacto Exosome in Medicube Exosome Shot is sourced from Lactobacillus, a type of beneficial bacteria that helps b

**Q: Is it normal for my face to tingle after application?**
A: It contains naturally derived micro-particle ingredients, which may cause a tingling sensation upon application. This is a natural reaction as the active ingredients are being delivered to the pores. Please adjust usage based on skin sensitivity.

**Q: Do I simply wash it off or do I maintain my regular skincare routine afterwards?**
A: This product is not meant to be rinsed off. Instead, it acts as a pathway to enhance skincare absorption, increasing the uptake of active ingredients by 242% compared to using cosmetics alone.

**Q: Will the Spicule(Hydrolyzed sponge) dissolve on the skin or be absorbed?**
A: The spicules are designed to naturally shed along with the dead skin over several days after application. Any residual product left behind will not be absorbed into your body; instead, it will naturally dissipate.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Timeless beauty in a bottle
*by H***S on March 6, 2025*

I purchased this product and it waz shipped out and delivered on time and with care. I used it right away and I want to give a detailed description about this item I received. I washed my face and I put a good amount on my face and it felt cool on the skin and right away you can feel it working. Rubbing it on the skin feels pretty good and than you start to feel a prickly feeling the more you work it into the skin, it doesn't hurt, it just feels like if you got fiberglass on the skin and you only feel that when touching the skin otherwise you wouldn't feel anything. A lil time went by and my skin started to get a slight sunburn look, it's exactly the same feeling as when you use dermaroller or stamp. It really is a needle less product and does the very same thing. Skin will feel warm cause blood is coming up to the skin which you want, to receive younger looking skin. It's plumping and the pores shrink and skin really looks amazing as it's working. The prickly feeling lasts throughout the night till next day and you wake up with a glow which feels good cause that's what we're looking for being age 53. I also added the medicube jelly collagen cream to give it an extra boost of hydration and adding the collagen it helps getting directly into the skin and the 2 together work wonders! This product helps us to deliver other products deeper into the skin so using the 2 is like a powerful regimen together! You will love the results. I used red light therapy to help as well and the 3 together makes the skin look amazing as well! It seems the more you touch your skin, the more you're allowing the product to work actively. Think of it as dermarolling and adding in serum as well as the red light therapy only the dermaroller has needles. I've used many products throughout time and dermaroller has given me the best results and these products here give exactly the same results only i love the outcome much better! I will continue using these products and highly recommend them to everyone who truly wants to get their glow back and look years younger in such a short time. My only regret is waiting to purchase these products but now I have them and plan on purchasing more. The night time mask is next. I compare this to frownies but much better due to me not ripping the patches from the skin and the mask is less invasive and works exactly the same, you're not missing any part of the skin when be able to apply it all over the face. I can't wait till I can update this after a couple of months of using these products. I had to explain in detail due to comments I've seen about how much it hurt cause it was the reason it took me longer to purchase this. It doesn't hurt and I hope you purchase it and try it cause I know you won't regret it at all. You'll be smiling cause as we age, our bodies change and I know I lost the natural glow i used to have and it's all back thanks to these products!! Thank you medicube for amazing products!! You have a lifetime customer here and with my skin only getting younger, I hope I can be someone that can help others to achieve the look we're all looking for at this age. I have and id love to see others look in the mirror and say wow! I like who I'm looking at😉

### ⭐⭐⭐⭐⭐ 7500 & No pain, love this light serum, doesn’t pill and I used shot mode first & booster mode with
*by L***A on May 3, 2025*

This is a great serum, I was kind of afraid of trying it at first since I bought the higher level version at 7500 and reading reviews saying that it hurt to put on but once I did try it I was very happily surprised. My skin had a glow to it after application and there was no pain when applying. I rubbed it on my face, cheek to check then forehead then patted it on my face to absorb better and it was more like a very light tingly feeling but only when I patted the spot I was applying the serum to. This isn’t sticky on my skin, there isn’t a scent to it and it’s not painful, it’s also very light weight and comes out of the pump looking like a thin see though gel looking serum so this is one I use first before my pdrn collagen serum or any of my other Medicube serums because this EXO serum seems to be the lightest and very helpful to your skin and pores. This 7500 EXO feels very hydrating as well, I put it on and took a nap and when I woke it felt like a moisturizer on my face but didn’t rub of onto my pillows as it went into my skin, I touched my face and could still feel the very light tingle ( I can’t think of a different name then tingle but it’s more like when you pat or rub it into your face you can feel a light sensation on you face, it’s quite pleasant though.) I am so glad I didn’t purchase the 2000 version because the 7500 it just perfect. You can feel it’s on your face but no pain, I also made sure to use the booster pro age-r on shot mode and used the pore toner pads before. I have sensitive skin and this didn’t bother my face but if you have extremely sensitive skin then maybe try the 2000 first. It really depends on your skin. Personally I wouldn’t waste on the 2000 and just buy the 7500 because it is so light feeling even though you can still feel it, it kinda feels nice when applying. This doesn’t pill on your face if you want to use the booster mode after or apply another serum over it. I used the salmon pdrn serum on booster mode after I waited about 30 minutes for the pore shot serum to dry, I then used the booster mode after for the pore shot by putting it on level 2 and moving it up towards my forehead and still no pain,. Then used the salmon pdrn serum ( highly recommend! ) over it, finishing the 5 min for booster mode and had a lovely glow with pink cheeks. I wish I tried this exosome spicule shot a long time ago, it’s lovely and not painful but you can feel and tell it’s working on your face. I finished with the cooling jelly moisturizer and a collagen liquid mask once the 2 ( patted on my face by hand ) layers of moisturizer had dried. The next day my face felt and looked great with a nice glow to it and a glasssy finish which I absolutely love about the Medicube products, they due all work and makes your face look younger, also helps get rid of fine lines. This serum is an amazing product to start with after applying the toner pad and if you have a shot mode appliance by Medicube make sure to due that first ( before toner ) because it opens your pores and helps the serum penetrate deeper as does the booster mode, it helps your products go deeper into your skin and also helps the serums dry faster as they penetrate your skin deeper, saves time when you’re doing your night routine and is now a staple for me each night. Great skincare products! I love Medicube products and they actually work as well at a great price point compared to other brands. I always update my reviews if something changes, so if my opinion changes about this product I will be updating. For now I can’t wait to try the salmon pdrn EXO shot next!

### ⭐⭐⭐⭐⭐ Medicube #1 on my list!!
*by D***F on July 15, 2026*

I just love this Medicube Pore Care, Its a Dead Skin Cell Removal & Smoothing Skin cream and it has Anti-Aging, Barrier Repair & Hydrating Treatment For Dull, Rough & Enlarged Pores it feeling like little needles in it. Makes your wrinkles and face look and feel better. I tried 2000 then went for the higher dose 7500 and you really feel the a big difference! Great product I would highly recommend.

## Frequently Bought Together

- medicube Zero Exosome Shot 7,500 PPM Spicule Facial Serum | Liquid Skin Booster Serum | Exosome, AHA+BHA+PHA | Pore Care, Dead Skin Cells, Skin Texture | Korean Skin Care 1.01 fl.oz
- Medicube Zero Pore Pads 2.0, Dual-Textured Facial Toner Pads for Exfoliation and Pore Care with 4.5% AHA Lactic Acid & 0.45% BHA Salicylic Acid, Ideal for All Skin Types, Korean Skin Care (70 Pads)
- medicube Collagen Jelly Cream- Niacinamide & Freeze-Dried Hydrolyzed Collagen - Boosts skin's barrier hydration and gives 24h Glow & Lifted Look - No artificial color, Korean skincare (3.71 fl.oz.)

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*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-08-06*