--- product_id: 49917744 title: "– E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis" brand: "e45" price: "R1411" currency: ZAR in_stock: true category: "E45" url: https://www.desertcart.co.za/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis store_origin: ZA region: South Africa --- # 5% Urea for deep hydration Long-lasting 24-hour moisture Dual-action anti-itch lauromacrogols – E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis **Brand:** e45 **Price:** R1411 **Availability:** βœ… In Stock ## Summary > ✨ Say goodbye to itch, hello to calm skin! πŸ’§ ## Quick Answers - **What is this?** – E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis by e45 - **How much does it cost?** R1411 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis) ## Best For - e45 enthusiasts ## Why This Product - Trusted e45 brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - β€’ **Instant Itch Relief:** Powerful lauromacrogols soothe irritation fastβ€”because itching is not an option. - β€’ **Hydrate & Heal All Day:** Locks in moisture with 5% urea for skin that stays soft and calm. - β€’ **Travel-Ready Skincare Essential:** Generous 500g pump bottle designed for easy, mess-free application anytime, anywhere. - β€’ **Dermatologist Trusted Since 1952:** Decades of expertise in treating eczema, dermatitis, and dry skin conditions. - β€’ **Gentle Enough for the Whole Family:** Perfume-free, non-greasy formula safe for adults and infants over 1 month. ## Overview E45 Itch Relief Cream is a dermatologist-tested, dual-action formula combining 5% urea and lauromacrogols to provide 24-hour hydration and fast relief from itching caused by eczema, dermatitis, and dry skin. Suitable for all ages and skin types, this unscented, non-greasy cream has been a trusted skincare staple since 1952, now available in a convenient 500g pump bottle for everyday use. ## Description Product Description E45 Itch Relief Cream contains an anti-itch ingredient, lauromacrogols, which treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions. Formulated with urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable. RB-M-01759. Ingredients Dimeticone, Phenyl Dimeticone, Liquid Paraffin, Cetyl Palmitate, Stearic Palmitic Acid, Octyldodecanol, Glycerol, Polysorbate, Carbomer, Trometamol, Benzyl Alcohol, Purified Water. P.when('A').execute(function(A) { A.on('a:expander:toggle_description:toggle:collapse', function(data) { window.scroll(0, data.expander.$expander[0].offsetTop-100); }); }); Directions Twist pump to open position, depress pump to dispense cream, twist back to lock, apply to the affected skin 2 times daily, if symptoms persist, consult your doctor, each use of the pump dispenses approx 4 g of cream, E45 Itch Relief Cream for pruritus, eczema, dermatitis, and scaling skin conditions, always read the label Safety Warning Avoid contact with eyes Box Contains 1 X E45 Itch Relief Cream - 500 g See more ## Features - TREAT ITCHING AND SKIN IRRITATION – E45 Itch Relief Cream is a dual action treatment for skin irritation and itching caused by dry skin conditions, eczema, dermatitis, pruritus, and scaling skin conditions - MOISTURISING AND ANTI-ITCH INGREDIENTS – E45 Itch Relief Cream is formulated with urea which helps your skin to retain moisturise and keeps it hydrated. Our cream is also dermatologically tested to provide effective relief for itchy skin - HOW TO USE – Apply to the affected skin area twice daily for effective relief for itching and skin irritation. Our cream is perfume free and can be used in all skin areas, body, face, and hands. Suitable for adults and infants over the age of 1 month - QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. It has proven dermatological expertise dedicated to vulnerable dry skin - HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 our cream was introduced to pharmacy and retail in 1980 ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B001EJOHUU | | ASIN | B001EJOHUU | | Active Ingredients | urea | | Age Range Description | Adult | | Benefits | Soothing | | Best Sellers Rank | 724 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 5 in Itching & Rash Treatments | | Brand Name | E45 | | Container Type | Bottle | | Country as Labeled | United Kingdom | | Customer Reviews | 4.6 4.6 out of 5 stars (3,441) | | Customer reviews | 4.6 4.6 out of 5 stars (3,441) | | Global Trade Identification Number | 17350087736737 | | Guaranteed software updates until | unknown | | Is discontinued by manufacturer | No | | Item Dimensions | 50 x 50 x 240 millimetres | | Item Form | Cream | | Item Highlight | 24-hour hydration with urea for moisture retention - Relieves itchy skin, perfume free & dermatologically tested | | Item Type Name | E45 Dermatological Itch Relief Cream 500g | | Item Volume | 500 Millilitres | | Item Weight | 550 Grams | | Item model number | 348713 | | Manufacturer | E45 | | Manufacturer | E45 | | Manufacturer Part Number | 285-3331 | | Material Type Free | Paraben Free | | Model Name | E45 Dermatological Itch Relief Cream, Moisturising Dual Action Treatment for Itchy and Irritated Skin, 500g | | Model Number | 348713 | | Number of Items | 1 | | Other Special Features of the Product | Travel Size | | Product Dimensions | 5 x 5 x 24 cm; 550 g | | Recommended Uses For Product | Eczema | | Scent Name | Unscented | | Skin Care Application Time | Anytime | | Skin Type | All | | Special Ingredients | Lauromacrogols 3.0%w/w, Urea 5.0%w/w | | Specific Uses For Product | Eczema | | Sun Protection | SPF 50 Sun Protection Factor (SPF) | | Target Use Body Part | Whole Body | | Unit Count | 500.0 gram | ## Product Details - **Active ingredients:** urea - **Age range (description):** Adult - **Brand:** E45 - **Item dimensions L x W x H:** 50 x 50 x 240 millimetres - **Item form:** Cream - **Item volume:** 500 Millilitres - **Number of items:** 1 - **Scent:** Unscented - **Skin type:** All - **Special feature:** Travel Size ## Images ![– E45 Itch Relief Cream 500g for Eczema, Dry Skin & Dermatitis - Image 1](https://m.media-amazon.com/images/I/51Y6C5624FL.jpg) ## Questions & Answers **Q: Is this antibacterial?** A: It does not state anywhere on the container that it is antibacterial. My mother has very sensitive skin and prone to itching and E45 itch relief cream helps her condition. **Q: What is the expiry date please** A: It is about three years or so. The actual expiry date is printed on the label, near the back , within a small blue printed area about one inch square. I expect it would last much longer. **Q: ordered 1 500 gr m itch reamand bill comes ?!Β£8; please correct it** A: THe price in UK is approximately Β£25 per 500ml **Q: Is this product good to use for prickly heat rash please** A: Hi there, Good question; Product should not be used on infected or inflamed skin. However we would suggest speaking to a health care professional and getting their advice to check if E45 Itch Relief Cream would be suitable for your specific needs.[ E45 Itch Relief Cream for pruritus, eczema, dermatitis, and scaling skin conditions. Always read the label.] ## Frequently Bought Together - E45 Itch Relief Cream 500G - E45 Wash Cream 250ml - E45 shower cream 200ml --- ## Why Shop on Desertcart? - πŸ›’ **Trusted by 1.3+ Million Shoppers** β€” Serving international shoppers since 2016 - 🌍 **Shop Globally** β€” Access 737+ million products across 21 categories - πŸ’° **No Hidden Fees** β€” All customs, duties, and taxes included in the price - πŸ”„ **15-Day Free Returns** β€” Hassle-free returns (30 days for PRO members) - πŸ”’ **Secure Payments** β€” Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** β€” Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.za/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis](https://www.desertcart.co.za/products/49917744-e45-itch-relief-cream-500g-for-eczema-dry-skin-dermatitis) --- *Product available on Desertcart South Africa* *Store origin: ZA* *Last updated: 2026-11-05*