---
product_id: 4932183
title: "Advantage II Medium Dog"
brand: "advantage"
price: "R1891"
currency: ZAR
in_stock: true
reviews_count: 8
category: "Advantage"
url: https://www.desertcart.co.za/products/4932183-advantage-ii-medium-dog
store_origin: ZA
region: South Africa
---

# Waterproof after 24 hours Kills fleas in 12 hours 30-day continuous protection Advantage II Medium Dog

**Brand:** advantage
**Price:** R1891
**Availability:** ✅ In Stock

## Summary

> 🐾 Stay ahead of fleas and keep your pup adventure-ready!

## Quick Answers

- **What is this?** Advantage II Medium Dog by advantage
- **How much does it cost?** R1891 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/4932183-advantage-ii-medium-dog)

## Best For

- advantage enthusiasts

## Why This Product

- Trusted advantage brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Month-Long Defense:** Keeps your dog protected for a full 30 days without reapplication
- • **Effortless Application:** Easy, no-prescription topical drops—no pills or collars needed
- • **Rapid Flea Elimination:** Starts killing fleas within 12 hours for fast relief
- • **Complete Flea Lifecycle Control:** Targets adult fleas, larvae, and eggs for total prevention
- • **Vet-Recommended & Fragrance-Free:** Trusted by professionals with a gentle, unscented formula

## Overview

Advantage II Medium Dog is a vet-recommended, fragrance-free topical flea treatment designed for dogs weighing 11-20 lbs and aged 7 weeks or older. It kills adult fleas, larvae, and eggs within 12 hours and provides 30 days of waterproof protection, ensuring total flea prevention and treatment with easy monthly application—no prescription required.

## Description

Advantage II Medium Dog is the vet-recommended prevention and treatment of flea and lice infestations in dogs. Advantage II Medium Dog flea treatment and prevention kills adult fleas, flea larvae and flea eggs to deliver total flea protection to your dog or puppy. In fact, within 12 hours of application, Advantage II Medium Dog topical treatment gets straight to work killing fleas through contact, so they don’t have to bite your dog to die.This 30-day treatment effectively breaks the flea life cycle, controlling existing flea and lice infestations and preventing further infestations all month long. Fleas not only cause discomfort; they can also pose other health risks. Monthly use of Advantage II Medium Dog is important to protect your dog against fleas that may cause transmission of tapeworms in dogs, Flea Allergy Dermatitis and flea bite anemia.That’s why Advantage II topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that Advantage II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. Advantage II Medium Dog flea and lice protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh 11 to 20 lbs. to use Advantage II Medium Dog.For the ultimate convenience in care, Advantage II Medium Dog is available over the counter – no prescription needed. And, you can stock up with a subscription for regular doorstep deliveries so you never miss a monthly treatment. Once Advantage II Medium Dog is applied, your dog is ready to get right back to exploring his favorite places – from the backyard to the dog park.Advantage II Medium Dog is a trademark of Elanco or its affiliates.

Review: Reliable protection for my girl! - ​Finding an effective flea treatment for a large dog can be a challenge, but Advantage II has always been my go-to. This 4-month supply for dogs 55+ lbs is perfect for keeping my dog protected throughout the season. It’s easy to apply, waterproof, and I love that it kills fleas at all life stages—larvae and eggs included—so we don't have to deal with any re-infestations. My order was delivered right on time on May 8th, and it's such a relief to have peace of mind knowing he's covered. Highly recommend for any large breed owners!
Review: Worked very well - This stuff works like magic a very well flea killer she is one happy dog!

## Features

- Vet recommended flea treatment and prevention for dogs at weighing 11 to 20 lbs., at least 7 weeks of age
- Kills adult fleas, flea larvae and flea eggs for total flea prevention and treatment
- Same-day effectiveness, kills fleas within 12 hours of application and keeps working for 30 days
- Easy-to-apply topical treatment, no prescription needed
- Fragrance-free formula, waterproof after 24 hours

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B004QREOYG |
| Active Ingredients | Imidacloprid, Pyriproxyfen |
| Age Range Description | 7 weeks and older |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #1,704 in Pet Supplies ( See Top 100 in Pet Supplies ) #17 in Dog Flea Drops |
| Brand | Advantage |
| Brand Name | Advantage |
| Customer Reviews | 4.5 out of 5 stars 19,168 Reviews |
| Dog Breed Size | Medium |
| Global Trade Identification Number | 00724089202673, 00724089617231, 10724089367584 |
| Included Components | 4 |
| Item Form | Topical |
| Item Type Name | Topical |
| Item Volume | 4 Milliliters |
| Item Weight | 22.68 g |
| Manufacturer | Elanco US Inc |
| Manufacturer Part Number | 86336758 |
| Model Number | 86336758 |
| Scent | Unscented |
| Scent Name | Unscented |
| Target Species | Dog |
| UPC | 724089202673 724089617231 724089378934 |
| Unit Count | 4 Count |
| Volume | 4 Milliliters |
| Warranty Description | No_warranty |

## Product Details

- **Active Ingredients:** Imidacloprid, Pyriproxyfen
- **Age Range (Description):** 7 weeks and older
- **Allergen Information:** Allergen-Free
- **Brand:** Advantage
- **Dog Breed Size:** Medium
- **Item Form:** Topical
- **Item Volume:** 4 Milliliters
- **Item Weight:** 0.05 Pounds
- **Scent:** Unscented
- **Unit Count:** 4 Count

## Images

![Advantage II Medium Dog - Image 1](https://m.media-amazon.com/images/I/71Uns06GOaL.jpg)
![Advantage II Medium Dog - Image 2](https://m.media-amazon.com/images/I/91ffMv-togL.jpg)
![Advantage II Medium Dog - Image 3](https://m.media-amazon.com/images/I/71E2+XSVnPL.jpg)
![Advantage II Medium Dog - Image 4](https://m.media-amazon.com/images/I/71h3X2fHJOL.jpg)
![Advantage II Medium Dog - Image 5](https://m.media-amazon.com/images/I/81uXyBYfp1L.jpg)

## Available Options

This product comes in different **Size, Style** options.

## Questions & Answers

**Q: My dog only goes out to get groomed every 3 months or to vet. Do I need to use this all the time or can I apply it 1 week before groom/vet day?**
A: This is a once a month topical treatment. You can apply prior to the appt. however it doesn't start to work until after the 1st 12 hours of being applied. 
Thank you. 
Heartland Vet Supply Customer Service

**Q: is this 4 mn or 6 mn / discrepancy in description**
A: There is an option for both 4 month and 6 month packages

**Q: Can I return this product?**
A: Hi. We recommend you contact the seller for a replacement or refund.

**Q: El producto es de bayer ? o es de elanco ?? porque el enunciado dice una cosa y la caja dice otra. esto es confuso !**
A: Hi. Elanco acquired Bayer Animal Health in 2020, including the Advantage II brand. 

To learn more about Advantage II and other Elanco products, visit PetBasics.Elanco.com.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Reliable protection for my girl!
*by J***K on May 13, 2026*

​Finding an effective flea treatment for a large dog can be a challenge, but Advantage II has always been my go-to. This 4-month supply for dogs 55+ lbs is perfect for keeping my dog protected throughout the season. It’s easy to apply, waterproof, and I love that it kills fleas at all life stages—larvae and eggs included—so we don't have to deal with any re-infestations. My order was delivered right on time on May 8th, and it's such a relief to have peace of mind knowing he's covered. Highly recommend for any large breed owners!

### ⭐⭐⭐⭐⭐ Worked very well
*by T***R on May 8, 2026*

This stuff works like magic a very well flea killer she is one happy dog!

### ⭐⭐⭐⭐⭐ Quality
*by H***H on May 24, 2026*

Excellent product

## Frequently Bought Together

- Advantage II Medium Dog Vet-Recommended Flea Treatment & Prevention | Dogs 11-20 lbs. | 4-Month Supply
- Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 4-Month Supply
- Advantage II Large Dog Vet-Recommended Flea Treatment & Prevention | Dogs 21-55 lbs. | 4-Month Supply

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---

*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-06-06*