---
product_id: 48784676
title: "Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml"
brand: "regenerate"
price: "R549"
currency: ZAR
in_stock: true
reviews_count: 8
category: "Regenerate"
url: https://www.desertcart.co.za/products/48784676-advanced-toothpaste-to-repair-tooth-enamel-for-strong-healthy-teeth
store_origin: ZA
region: South Africa
---

# 3x stronger teeth vs standard toothpaste NR-5 patented mineral technology Clinically proven enamel regeneration Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml

**Brand:** regenerate
**Price:** R549
**Availability:** ✅ In Stock

## Summary

> 🦷 Elevate your smile game — because your enamel deserves the future-proof treatment.

## Quick Answers

- **What is this?** Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml by regenerate
- **How much does it cost?** R549 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/48784676-advanced-toothpaste-to-repair-tooth-enamel-for-strong-healthy-teeth)

## Best For

- regenerate enthusiasts

## Why This Product

- Trusted regenerate brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Boost Your Results:** Combine with REGENERATE Advanced Enamel Serum to amplify enamel strengthening effects by 43%.
- • **Daily Ritual, Elevated:** Use twice daily in place of your regular toothpaste for continuous enamel repair and cavity protection.
- • **Triple Strength Defense:** Delivers 3x stronger teeth compared to regular fluoride toothpaste, future-proofing your smile against acid attacks.
- • **Science-Backed Innovation:** Powered by patented NR-5™ technology that integrates fresh enamel minerals directly onto your teeth.
- • **Rebuild Your Smile’s Armor:** Clinically proven to regenerate enamel mineral and reverse early erosion, protecting your teeth from sensitivity and yellowing.

## Overview

Regenerate Advanced Toothpaste harnesses patented NR-5™ technology to clinically regenerate tooth enamel mineral, reversing early enamel erosion that causes sensitivity, yellowing, and weakening. With regular twice-daily use, it strengthens teeth up to 3 times more than standard fluoride toothpaste, restores natural whiteness, and protects against cavities. For enhanced results, pairing with the Advanced Enamel Serum boosts enamel repair by 43%, making it a scientifically proven solution for maintaining a strong, healthy smile.

## Description

Product Description Every smile has a common and unseen enemy: enamel erosion. In fact, 80% of common tooth problems such as Yellowing, Sensitivity, Weakness, Transparency, are caused by enamel erosion and acid attacks. Enamel erosion happens to everyone, at all ages. Even healthy food and drinks can trigger acid attacks, which can cause enamel erosion. REGENERATE™ Enamel Science Advanced Toothpaste is powered by a revolutionary and internationally patented NR-5™ technology that is clinically proven to help regenerate enamel mineral* and reverse the early erosion process. Thanks to its unique formulation, the Advanced Toothpaste has distinctive product characteristics: a dense formula with a rich texture which reacts unleashing its regenerative power when brushing your teeth. With each use of Advanced Toothpaste, the unique NR-5™ ingredients form a fresh supply of enamel mineral. These wrap and integrate onto the teeth and regenerate enamel mineral* with exactly the same mineral tooth enamel is made of. Use this enamel strengthening toothpaste daily, in place of your normal toothpaste, to keep your teeth strong and healthy as well as to restore your teeth’s original whiteness. *Acts on early invisible stages of enamel erosion by restoring its mineral content with regular use. Clinically proven. ** Based on an in vitro test measuring enamel hardness versus standard fluoride toothpaste. ***As demonstrated in a 3 day in vitro test measuring enamel micro hardness: Combined use of toothpaste and serum vs. toothpaste only. Ingredients Glycerin, Calcium Silicate, PEG-8, Hydrated Silica, Trisodium Phosphate, Sodium Phosphate, Aqua, PE-60, Sodium Lauryl Sulfate, Sodium Monofluorophospate, AromaFlavour, Synthetic Fluorphlogopite, Sodium Saccharin, Polyacrylic Acid, Tin Oxide, Limonene, C177891 Directions Use this enamel strengthening toothpaste twice daily, in place of your normal toothpaste Safety Warning Avoid swallowing, keep away from children, and avoid contact with eyes or sensitive areas. Box Contains 1x REGENERATE Enamel Science™ Advanced Toothpaste Manufacturer Contact Information Unilever Dept ER Wirral CH63 3JW UK

Review: Actually feels different from regular toothpaste - I wasn’t expecting much because a lot of “repair” toothpastes feel like marketing, but this one genuinely made my teeth feel smoother and less sensitive after about a week. The texture is nice, not too gritty, and it leaves a really clean feeling without being overpowering. The taste is fresh but a bit more “clinical” than minty-fancy toothpaste. If you love super strong mint, this may feel a little plain. Best tip: don’t rinse too much after brushing. Leaving a little on the teeth seems to work better, especially for sensitivity and enamel care. A bit expensive for the size, but if your teeth are sensitive or feel worn down from coffee, whitening products, or acidic drinks, it’s worth trying.
Review: The only toothpaste I keep coming back to - I started using this after dealing with tooth sensitivity, and within about a week I noticed a big improvement. The sensitivity went away and I’ve stuck with this brand ever since because I don’t want it coming back. I also looked into the technology used in the toothpaste before buying it, rather than just relying on the marketing, and it seems to have a proper basis behind the claims. Obviously everyone’s teeth are different, but for me it has genuinely worked. It tastes pleasant, leaves my mouth feeling clean and has become my regular everyday toothpaste.

## Features

- 80% of common tooth problems such as sensitivity, transparency and yellowing are caused by enamel erosion and acid attacks
- REGENERATE Enamel Science is the first oral care system able to regenerate tooth enamel mineral*, reversing the early enamel erosion process, keeping teeth healthy and strong to future-proof your smile
- Its unique NR-5 ingredients combine to form a fresh supply of tooth enamel minerals which wrap and integrate onto teeth
- Helps protect against cavities, restore original whiteness and provides 3 times stronger teeth**
- Use REGENERATE Advanced Toothpaste twice daily, in place of your regular toothpaste
- For best results, use in combination with REGENERATE Advanced Enamel Serum to boost effectiveness by 43%***

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00P7SIVAQ |
| Active Ingredients | fluoride |
| Age Range Description | Adult |
| Age range (description) | Adult |
| Benefits | REGENERATE Enamel Science regenerates tooth mineral and reverses early enamel erosion, keeping teeth healthy strong - for a beautiful smile in the future. |
| Best Sellers Rank | 645 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 38 in Toothpastes |
| Brand | Regenerate |
| Brand Name | Regenerate |
| Capacity | 75 ml |
| Country Of Origin | United Kingdom |
| Customer Reviews | 4.4 out of 5 stars 9,062 Reviews |
| Flavour | Mint |
| Global Trade Identification Number | 08712561170277 |
| Item Dimensions | 17.8 x 0.6 x 25.4 centimetres |
| Item Form | Paste |
| Item Part Number | 8712561170277 |
| Item Weight | 105 Grams |
| Item form | Paste |
| Manufacturer | Unilever |
| Manufacturer Contact Information | Unilever Dept ER Wirral CH63 3JW UK |
| Manufacturer Part Number | REG001 |
| Material Features | Natural |
| Material Type Free | Fluoride Free |
| Material feature | Natural |
| Model Number | REG001 |
| Number of Items | 1 |
| Package Quantity | 1 |
| Package Type Name | Tube |
| Packaging Feature | Wrap |
| Recommended Uses For Product | Tooth Enamel Repair, Cavity Protection, Whitening, Enamel Protection |
| Target Audience | Child. |
| UPC | 072671103014 |
| Unit Count | 75.0 millilitre |

## Product Details

- **Age range (description):** Adult
- **Brand:** Regenerate
- **Flavour:** Mint
- **Item form:** Paste
- **Item package quantity:** 1
- **Item weight:** 105 Grams
- **Material Type Free:** Fluoride Free
- **Material feature:** Natural
- **Target audience:** Child.

## Images

![Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml - Image 1](https://m.media-amazon.com/images/I/71CdxiDTI0L.jpg)
![Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml - Image 2](https://m.media-amazon.com/images/I/61mKX-8InEL.jpg)
![Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml - Image 3](https://m.media-amazon.com/images/I/913Ptgv8kqL.jpg)
![Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml - Image 4](https://m.media-amazon.com/images/I/61BPF+sRklL.jpg)
![Advanced Toothpaste to repair tooth enamel for strong, healthy teeth 75ml - Image 5](https://m.media-amazon.com/images/I/71r+fcV97nL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: What are the active ingredients?**
A: Here is the full list of ingredients - Glycerin, Calcium Silicate, Peg-8, Hydrated Silica, Trisodium Phosphate, Sodium Phosphate, Aqua, Peg-60, Sodium Lauryl Sulfate, Sodium Monofluorphosphate, Aroma, Synthetic Fluorphlogopite, Sodium Saccharin, Polyacrylic Acid, Tin Oxide, Limonene, CI 77891.

**Q: is there actual proof of it literally regenerate the enamel?**
A: Regenerate uses a combination of calcium silicate and sodium phosphate to form hydroxyapatite. Hydroxyapatite helps make up bones and teeth in human anatomy.Here's a scientific research article that claims nano hydroxyapatite helps restore tooth enamel. They use Biorepair in the research article, but I'm relatively certain it can refer to Regenerate too.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155874/

**Q: Does it have fluoride and if so, how much?**
A: These are the ingredients: Glycerin, Calcium Silicate, Peg-8, Hydrated Silica, Trisodium Phosphate, Sodium Phosphate, Aqua, Peg-60, Sodium Lauryl Sulfate, Sodium Monofluorophosphate, Aroma, Synthetic Fluorphlogopite, Sodium Saccharin, Polyacrylic Acid, Tin Oxide, Limonene, Ci 77891. 

It doesn’t say “Fluoride” but there is something called “Fluorphlogopite”.

**Q: Where is this made ??  Outer box and tube do not say!!**
A: I am pretty sure there  are 2 types Italian and Japan. This brand I THINK is the Italian. The other one is Apagard Premio which I believe to be the Japan.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Actually feels different from regular toothpaste
*by C***N on 8 May 2026*

I wasn’t expecting much because a lot of “repair” toothpastes feel like marketing, but this one genuinely made my teeth feel smoother and less sensitive after about a week. The texture is nice, not too gritty, and it leaves a really clean feeling without being overpowering. The taste is fresh but a bit more “clinical” than minty-fancy toothpaste. If you love super strong mint, this may feel a little plain. Best tip: don’t rinse too much after brushing. Leaving a little on the teeth seems to work better, especially for sensitivity and enamel care. A bit expensive for the size, but if your teeth are sensitive or feel worn down from coffee, whitening products, or acidic drinks, it’s worth trying.

### ⭐⭐⭐⭐⭐ The only toothpaste I keep coming back to
*by T***E on 14 July 2026*

I started using this after dealing with tooth sensitivity, and within about a week I noticed a big improvement. The sensitivity went away and I’ve stuck with this brand ever since because I don’t want it coming back. I also looked into the technology used in the toothpaste before buying it, rather than just relying on the marketing, and it seems to have a proper basis behind the claims. Obviously everyone’s teeth are different, but for me it has genuinely worked. It tastes pleasant, leaves my mouth feeling clean and has become my regular everyday toothpaste.

### ⭐⭐⭐⭐ Better results than the leading brand of enamel repair toothpaste
*by T***M on 31 December 2024*

I thought I might have fallen for marketing spiel with the "NR-5 technology" stuff, just buying yet another toothpaste with fluroide in it. However, having tried it the results have been good, and doing a bit of research into the ingredients I can understand why. The idea is that the calcium silicate and trisodium phosphate work together with the fluoride (sodium monofluorophosphate) to become fluorapatite, a form of hydroxyapatite and the mineral that makes up tooth enamel. Certainly better results for me than Sensodyne ProEnamel. The negative is that, like Sensodyne, it also contains surprisingly abrasive Hydrated Silica - fine for those with only mild sensitivity, but an unnecessary addition if you've got real issues with thin/worn teeth. I apply it topically, leave for a few minutes, then brush very gently brush, being sure to leave the paste on my teeth rather than washing away with water. Still, not quite as effective as Elmex Sensitive Professional toothpaste with arginine (available on the continent but not typically in the UK)

## Frequently Bought Together

- Regenerate Enamel Science Advanced Toothpaste 75Ml
- Viva Doria Tooth Enamel Remineralizing Liquid, Protects Tooth Enamel and Helps Keep Gum Healthy 1 fl oz
- Sensodyne Pronamel Intensive Enamel Repair Toothpaste for Sensitive Teeth, to Reharden and Strengthen Enamel, Extra Fresh - 3.4 Ounces

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*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-08-14*