--- product_id: 48147815 title: "Itch Relief 100g – Anti Itch Cream for Skin Irritation – Non-Greasy to Relieve Itching – Eczema Dermatitis Cream – Instantly Soothes and Calms Skin" brand: "e45" price: "R573" currency: ZAR in_stock: true category: "E45" url: https://www.desertcart.co.za/products/48147815-itch-relief-100g-anti-itch-cream-for-skin-irritation-non store_origin: ZA region: South Africa --- # 3% Lauromacrogols for fast itch relief 5% Urea for deep hydration Non-greasy, quick absorption Itch Relief 100g – Anti Itch Cream for Skin Irritation – Non-Greasy to Relieve Itching – Eczema Dermatitis Cream – Instantly Soothes and Calms Skin **Brand:** e45 **Price:** R573 **Availability:** ✅ In Stock ## Summary > ✨ Calm your skin, conquer your day! ## Quick Answers - **What is this?** Itch Relief 100g – Anti Itch Cream for Skin Irritation – Non-Greasy to Relieve Itching – Eczema Dermatitis Cream – Instantly Soothes and Calms Skin by e45 - **How much does it cost?** R573 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/48147815-itch-relief-100g-anti-itch-cream-for-skin-irritation-non) ## Best For - e45 enthusiasts ## Why This Product - Trusted e45 brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Hydrate to Heal:** Urea locks in moisture, reducing dryness and accelerating skin recovery. - • **Versatile & Gentle:** Perfume-free formula safe for face, hands, and body—ideal for daily use and all skin types. - • **Lightweight & Non-Greasy:** Absorbs quickly without residue—perfect for busy professionals on the go. - • **Dual-Action Soothing Power:** Combats itching and irritation from eczema, dermatitis, and dry skin with proven active ingredients. - • **Trusted Dermatological Expertise:** 60 years of skincare innovation trusted by millions for sensitive and vulnerable skin. ## Overview E45 Itch Relief Cream is a dermatologist-tested, non-greasy formula combining 5% urea and 3% lauromacrogols to instantly soothe itching and irritation caused by eczema, dermatitis, and dry skin. Trusted for over 60 years, it deeply moisturizes while calming sensitive skin, making it a must-have for professionals seeking fast, effective relief without compromise. ## Description Product Description E45 Itch Relief Cream contains an anti-itch ingredient, lauromacrogols, which treats and soothes the itching caused by eczema, dermatitis, pruritus and scaling skin conditions. Formulated with urea, a moisturiser found naturally within the skin, E45 Itch Relief Cream is non-greasy, moisturising and can soothe the skin and leave it feeling calm and comfortable. Ingredients Active ingredients: Urea 5.0% w/w, lauromacrogols 3.0% w/w. Also contains: Dimethicone, phenyl dimethicone, liquid paraffin, cetyl palmitate, stearic palmitic acid, octyldodecanol polysorbate, carbomer, glycerol, benzyl alcohol, trometamol, purified water. P.when('A').execute(function(A) { A.on('a:expander:toggle_description:toggle:collapse', function(data) { window.scroll(0, data.expander.$expander[0].offsetTop-100); }); }); Directions Ensure the affected area is clean and dry before application. Take a small amount of E45 Itch Relief Cream onto your fingertips. Gently massage the cream into the affected skin until fully absorbed. Use as needed, up to three times daily, or as directed by a healthcare professional. Wash hands thoroughly after application. Avoid contact with eyes. If contact occurs, rinse thoroughly with water. Discontinue use if irritation or rash develops. Store in a cool, dry place and keep out of reach of children. For external use only. Safety Warning For external use only. Avoid ingestion. Keep out of reach of children. Avoid contact with eyes. If contact occurs, rinse thoroughly with water. Discontinue use if irritation or rash develops. Do not apply to broken or irritated skin. Store in a cool, dry place away from direct sunlight. Consult a healthcare professional before use if pregnant, nursing, or have a medical condition. Use only as directed. If symptoms persist, seek medical advice. This product is not intended to diagnose, treat, cure, or prevent any disease. Keep packaging for future reference. Box Contains 1 x E45 Itch Relief Cream - 100 g Manufacturer Contact Information MA holder: Karo Pharma AB, Stockholm, Sweden. Reckitt Benckiser Healthcare (UK) Ltd, HU8 7DS. RB NL Brands B.V., WTC Schiphol Airport, Schiphol Boulevard 207, 1118 BH Schiphol, Netherlands. See more ## Features - TREAT ITCHING AND SKIN IRRITATION – E45 Itch Relief Cream is a dual action treatment for skin irritation and itching caused by dry skin conditions, eczema, dermatitis, pruritus, and scaling skin conditions - MOISTURISING AND ANTI-ITCH INGREDIENTS – E45 Itch Relief Cream is formulated with urea which helps your skin to retain moisturise and keeps it hydrated. With the skin less itchy, you will scratch less and therefore speed up the healing process - HOW TO USE – Apply to the affected skin area twice daily for effective relief for itching and skin irritation. Our cream is perfume free can be used in all skin areas such as the body, face, and hands - QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. It has proven dermatological expertise dedicated to vulnerable dry skin - HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 our cream was introduced to pharmacy and retail in 1980 ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B001PMM1LI | | ASIN | B001PMM1LI | | Active Ingredients | Lauromacrogols 3.0% w/w and Urea 5.0% w/w | | Allergen Information | Contains: Almonds Free | | Benefits | Soothing | | Best Sellers Rank | 1,250 in Health & Personal Care ( See Top 100 in Health & Personal Care ) 2 in Cortisone Treatments | | Brand Name | E45 | | Container Type | Box | | Customer Reviews | 4.5 4.5 out of 5 stars (8,503) | | Customer reviews | 4.5 4.5 out of 5 stars (8,503) | | Global Trade Identification Number | 05000158426115 | | Guaranteed software updates until | unknown | | Included Components | Active Substance Combinations | | Is discontinued by manufacturer | No | | Item Form | Cream | | Item Volume | 100 Millilitres | | Item Weight | 100 Grams | | Item model number | 348712 | | Language | English | | Manufacturer | Reckitt Benckiser | | Manufacturer | Reckitt Benckiser | | Manufacturer Contact Information | MA holder: Karo Pharma AB, Stockholm, Sweden. Reckitt Benckiser Healthcare (UK) Ltd, HU8 7DS. RB NL Brands B.V., WTC Schiphol Airport, Schiphol Boulevard 207, 1118 BH Schiphol, Netherlands. | | Manufacturer Part Number | 348712 | | Model Number | 348712 | | Number of Items | 1 | | Product Dimensions | 15.39 x 5.41 x 5 cm; 100 g | | Scent Name | Unscented | | Size | 100 g (Pack of 1) | | Skin Type | Dry, Eczema-prone | | Target Use Body Part | Whole Body | | UPC | 802645851623 885226307634 885265452944 709102173284 722532073948 754495232384 | | Unit Count | 100.0 gram | ## Product Details - **Brand:** E45 - **Item form:** Cream - **Product benefits:** Soothing - **Scent:** Unscented - **Skin type:** Dry, Eczema-prone ## Images ![Itch Relief 100g – Anti Itch Cream for Skin Irritation – Non-Greasy to Relieve Itching – Eczema Dermatitis Cream – Instantly Soothes and Calms Skin - Image 1](https://m.media-amazon.com/images/I/61ared2dNGL.jpg) ## Available Options This product comes in different **Size** options. ## Questions & Answers **Q: Anyone use it for after trimming chest hair?** A: No I just use it for itchy skin **Q: Does it work for itching armpit** A: Hi there, Good question; Product should not be used on infected or inflamed skin. However we would suggest speaking to a health care professional and getting their advice to check if E45 Itch Relief Cream would be suitable for your specific needs.[ E45 Itch Relief Cream for pruritus, eczema, dermatitis, and scaling skin conditions. Always read the label.] **Q: Suitable after radiotherapy?** A: Didn't work for me. Active Silver Magic Gel was very effective but it costs a fortune. **Q: Can I use e45 itch relief creme on my face** A: I would do a ‘patch test’ first but see no reason why not. E45 is I think, a recognised name in beauty care. It saw me through two pregnancies without a single stretch mark. And it certainly soothed my incredibly itchy legs. ## Frequently Bought Together - E45 Itch Relief Cream 100g - Balneum Plus Cream, 100 g - E45 shower cream 200ml --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.za/products/48147815-itch-relief-100g-anti-itch-cream-for-skin-irritation-non](https://www.desertcart.co.za/products/48147815-itch-relief-100g-anti-itch-cream-for-skin-irritation-non) --- *Product available on Desertcart South Africa* *Store origin: ZA* *Last updated: 2026-09-26*