---
product_id: 429877044
title: "Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)"
brand: "designs for health"
price: "R2921"
currency: ZAR
in_stock: true
reviews_count: 5
category: "Designs For Health"
url: https://www.desertcart.co.za/products/429877044-homocysteine-supreme-methylated-b-vitamins-with-riboflavin-b6-b12-folate
store_origin: ZA
region: South Africa
---

# Vegetarian, Non-GMO, allergen-free formula Methylated B Vitamins for brain & nerve support Optimizes homocysteine for heart health Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)

**Brand:** designs for health
**Price:** R2921
**Availability:** ✅ In Stock

## Summary

> 🧬 Elevate your wellness game with the ultimate methylation powerhouse!

## Quick Answers

- **What is this?** Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules) by designs for health
- **How much does it cost?** R2921 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/429877044-homocysteine-supreme-methylated-b-vitamins-with-riboflavin-b6-b12-folate)

## Best For

- designs for health enthusiasts

## Why This Product

- Trusted designs for health brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Heart & Brain Synergy:** Clinically designed to support cardiovascular function and cognitive clarity
- • **Bioavailable B Vitamins:** Includes P5P B6, methylfolate, and methylcobalamin for maximum absorption and efficacy
- • **Clean & Conscious Formula:** Vegetarian, soy-free, gluten-free, and non-GMO to fit your clean-living lifestyle
- • **Precision Methylation Boost:** Advanced methylated B complex with L-serine & TMG for superior homocysteine metabolism
- • **Practitioner-Trusted Quality:** Top-rated by functional medicine experts for reliable, science-backed supplementation

## Overview

Designs for Health Homocysteine Supreme delivers a premium blend of methylated B vitamins, L-serine, and TMG to optimize homocysteine metabolism, supporting heart and brain health. This vegetarian, non-GMO formula features bioavailable forms of B6, B12, and folate, trusted by functional medicine practitioners for superior absorption and clinically effective results.

## Description

Buy Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules) online on desertcart.ae at best prices. ✓ Fast and free shipping ✓ free returns ✓ cash on delivery available on eligible purchase.

Review: At last, a formulation with all bioavailable forms of B vitamins with added TMG. Even the B6 is in the form of P-5-P, which is important for nerve health. However, I bought this to help bring down my Homocysteine, which was elevated even when taking other B Complex formulas. This really did what it says on the label as it brought my Homocysteine level back down to a healthy as shown by my blood tests. I will keep buying this as it works.
Review: Recommended by my functional medicine doctor, and it’s been great so far! Excellent quality and value, and I don’t notice any taste when taking it—which is a big plus.

## Features

- Methylation Support - A modified methylated B complex with L-serine and TMG, which are known to facilitate the efficient metabolism of homocysteine and normal methylation.*
- Promotes Heart & Brain Health - An optimally functioning homocysteine pathway plays a role in biochemical reactions, such as detoxification, healthy immune support, ideal joint and cartilage structure, brain health and cardiovascular health.*
- Premium B Vitamins & TMG for Superior Absorption - Supplies a methylated folate and B12 supplement, along with P5P vitamin B6 and riboflavin. Includes Trimethylglycine to support normal methylation.*
- Vegetarian & Non-GMO - Vegetarian-friendly and made without soy, gluten, GMOs or soy. Take 2 capsules per day with meals or as directed by your health-care practitioner.
- Clinically-Trusted Care - DFH is the #1 practitioner supplement brand recommended by functional medicine professionals and the #1 practitioner supplement brand personally trusted by functional medicine professionals.**

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0050DZF2U |
| ASIN  | B0050DZF2U |
| Additives | Amino Acids |
| Age Range Description | Adult |
| Allergen Information | Allergen-Free |
| Best Sellers Rank | #46,673 in Health ( See Top 100 in Health ) #496 in Vitamin B Supplements |
| Brand | designs for health |
| Customer Reviews | 4.8 4.8 out of 5 stars (576) |
| Customer reviews | 4.8 4.8 out of 5 stars (576) |
| Date First Available | 22 February 2022 |
| Format | Capsule |
| Is Discontinued By Manufacturer  | No |
| Manufacturer  | Designs for Health |
| Manufacturer reference  | HYS120-AZ |
| Product Dimensions  | 7.62 x 7.62 x 12.7 cm; 1 g |
| Serving Recommendation | 2 Capsules |
| Serving Size | 1 capsules |
| Units | 1.0 Count |

## Product Details

- **Brand:** designs for health
- **Diet type:** Vegetarian
- **Flavour:** Unflavored
- **Item form:** Capsule
- **Primary supplement type:** sulfur

## Images

![Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules) - Image 1](https://m.media-amazon.com/images/I/71wrGypNZNL.jpg)

## Questions & Answers

**Q: Curious why NAC was removed from the ingredients.**
A: Not just NAC, but zinc,B2, serine and chloline dihydrohen citrate

**Q: Does the Homocysteine Supreme contain turmeric?**
A: No, it contains riboflavin, vit. B-6, folate,vit. B-12, trimethylglycine, and L-serine. additional ingredients are cellulose/microcrystalline cellulose, ascorbyl palmitate, dicalcium phosphate, and silicon dioxide

**Q: Designs for health is the product manufacturer - who is the seller on Amazon?**
A: It's sold by the Designs for Health store on Amazon.

**Q: Does this product contain Bromelain in it?**
A: I just checked the label and I don't see Bromelain mentioned anywhere on the label. Hope this helps you.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by K***S on 30 January 2026*

At last, a formulation with all bioavailable forms of B vitamins with added TMG. Even the B6 is in the form of P-5-P, which is important for nerve health. However, I bought this to help bring down my Homocysteine, which was elevated even when taking other B Complex formulas. This really did what it says on the label as it brought my Homocysteine level back down to a healthy as shown by my blood tests. I will keep buying this as it works.

### ⭐⭐⭐⭐⭐ Review
*by T***. on 18 October 2025*

Recommended by my functional medicine doctor, and it’s been great so far! Excellent quality and value, and I don’t notice any taste when taking it—which is a big plus.

### ⭐⭐⭐⭐⭐ Review
*by J***Y on 27 August 2025*

Excellent product for high homocysteine levels, have had no negative side effects at all, and it does provide a small boost of energy, very smooth effect, and significantly lowered my homocysteine levels.

## Frequently Bought Together

- Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin, B6, B12, Folate, L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (120 Capsules)
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*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-03-08*