---
product_id: 331669350
title: "S3 SEB Shampoo 16.9 oz (500 mL) - Relief for Seborrhea in Dogs and Cats (Helps with Oily to Flaky Skin) | Seborrhea Treatment for Dogs & Cats, Helps Control Dandruff, Unpleasant Odors & Oily/Flaky Skin, 0.5% Ophytrium, 16.9 fl oz"
brand: "douxo"
price: "R1395"
currency: ZAR
in_stock: true
reviews_count: 5
category: "Douxo"
url: https://www.desertcart.co.za/products/331669350-s3-seb-shampoo-16-9-oz-500-ml-relief-seborrhea
store_origin: ZA
region: South Africa
---

# 0.5% Ophytrium active Clinically proven for pets 500 mL soothing formula S3 SEB Shampoo 16.9 oz (500 mL) - Relief for Seborrhea in Dogs and Cats (Helps with Oily to Flaky Skin) | Seborrhea Treatment for Dogs & Cats, Helps Control Dandruff, Unpleasant Odors & Oily/Flaky Skin, 0.5% Ophytrium, 16.9 fl oz

**Brand:** douxo
**Price:** R1395
**Availability:** ✅ In Stock

## Summary

> 🐕✨ Transform your pet’s skin and coat with vet-trusted relief!

## Quick Answers

- **What is this?** S3 SEB Shampoo 16.9 oz (500 mL) - Relief for Seborrhea in Dogs and Cats (Helps with Oily to Flaky Skin) | Seborrhea Treatment for Dogs & Cats, Helps Control Dandruff, Unpleasant Odors & Oily/Flaky Skin, 0.5% Ophytrium, 16.9 fl oz by douxo
- **How much does it cost?** R1395 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/331669350-s3-seb-shampoo-16-9-oz-500-ml-relief-seborrhea)

## Best For

- douxo enthusiasts

## Why This Product

- Trusted douxo brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Dual-Pet Power:** Perfectly safe and effective for both dogs and cats
- • **Sebum Control Mastery:** Normalizes oily skin to banish dandruff and odors
- • **Hydrating & Detangling:** Leaves coats irresistibly soft, shiny, and manageable
- • **Hypoallergenic & Clean:** Free from parabens, phthalates, and sulfates for sensitive skin
- • **Vet-Recommended Formula:** Trusted #1 non-prescription choice by U.S. veterinarians

## Overview

Douxo S3 SEB Shampoo is a 500 mL hypoallergenic, unscented treatment shampoo formulated with 0.5% Ophytrium to effectively control seborrhea symptoms in dogs and cats. Clinically proven to reduce excess sebum, dandruff, and unpleasant odors while hydrating and detangling fur, it’s the #1 non-prescription choice recommended by U.S. veterinarians for managing oily to flaky skin conditions.

## Description

Formulated to remove excess sebum, oils and flaky skin buildup. Helps reduce dandruff and deodorize. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the #1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs and cats with seborrheic dermatological diseases.

Review: Na - Na
Review: Duoxo - Es un shampoo para la piel de mi perrita que padece de ictiasis

## Features

- DOUXO S3 SEB Shampoo is for dogs or cats with oily to flaky skin
- Helps control dandruff and odor by normalizing sebum production while hydrating the skin
- Detangles the fur and leaves the coat soft and shiny
- Clinically proven in dogs to reduce dandruff, excess sebum, and unpleasant odors
- For best results use with DOUXO S3 SEB Mousse

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B09478VXZP |
| Allergen Information | Hypoallergenic |
| Best Sellers Rank | #10,956 in Pet Supplies ( See Top 100 in Pet Supplies ) #117 in Dog Shampoos |
| Brand | DOUXO |
| Brand Name | DOUXO |
| Customer Reviews | 4.6 out of 5 stars 643 Reviews |
| Included Components | Shampoo |
| Item Form | Liquid |
| Item Type Name | Shampoos & Conditioners |
| Item form | Liquid |
| Liquid Volume | 16.9 Fluid Ounces |
| Manufacturer | Douxo S3 |
| Manufacturer Part Number | D98620E |
| Material Type Free | Paraben Free, Phthalate Free, Sulfate Free |
| Material type free | Paraben Free, Phthalate Free, Sulfate Free |
| Model Number | D98620E |
| Package Size Name | 16.9 fl oz |
| Pet Type | Cat |
| Product Benefits | Relieves seborrhea in the skin of dogs and cats, helping to control the oil |
| Product benefits | Relieves seborrhea in the skin of dogs and cats, helping to control the oil |
| Recommended Uses For Product | Irritated Skin |
| Recommended uses for product | Irritated Skin |
| Scent | Unscented |
| Scent Name | Unscented |
| Special Ingredients | Ophytrium 0.5% |
| Target Species | Dog and Cat |
| UPC | 850002593464 |
| Unit Count | 499.79 Milliliters |

## Product Details

- **Brand:** DOUXO
- **Scent:** Unscented
- **Product benefits:** Relieves seborrhea in the skin of dogs and cats, helping to control the oil
- **Recommended uses for product:** Irritated Skin
- **Material type free:** Paraben Free, Phthalate Free, Sulfate Free

## Images

![S3 SEB Shampoo 16.9 oz (500 mL) - Relief for Seborrhea in Dogs and Cats (Helps with Oily to Flaky Skin) | Seborrhea Treatment for Dogs & Cats, Helps Control Dandruff, Unpleasant Odors & Oily/Flaky Skin, 0.5% Ophytrium, 16.9 fl oz - Image 1](https://m.media-amazon.com/images/I/61yO01F72XL.jpg)

## Questions & Answers

**Q: Is this a shampoo or mousse?  Description title line says shampoo, but item form lists it as mousse.**
A: This is a shampoo in a pump bottle.

**Q: My bedroom reeks of an odor from my German Shorthair Pointer even after a bath and thorough room cleaning  wondering if this may help?**
A: This shampoo definitely helped with our dogs bad body odor.  You may also want to treat your dog for fungus infection.  Our dog continued to smell badly until I treated him the same way you would treat athlete’s foot or a yeast infection

**Q: Can I use this on my pet mouse?**
A: No but you can probably use baby shampoo or even dawn.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Na
*by E***Z on 3 March 2025*

Na

### ⭐⭐⭐⭐⭐ Duoxo
*by M***O on 14 September 2024*

Es un shampoo para la piel de mi perrita que padece de ictiasis

### ⭐⭐⭐⭐⭐ The Shampoo That Turned My Greaseball Into a Show Dog
*by E***G on 9 September 2025*

I bought Douxo S3 Seb Shampoo for my bulldog, who had developed a persistent case of oily seborrhea that made him smell like a forgotten gym sock and look like he’d been dipped in fryer grease. We’d tried everything—medicated wipes, antifungal sprays, even vet-prescribed shampoos that smelled like chemical warfare. Nothing worked for more than a day. Then came Douxo. The first thing I noticed was the texture: thick, creamy, and easy to lather. It didn’t run off his coat like water on wax. I massaged it in and let it sit for the recommended 10 minutes, which he tolerated surprisingly well thanks to the mild scent—clean, almost herbal, and not remotely medicinal. After rinsing, his coat felt softer, less greasy, and the usual sour odor was gone. Not masked—gone. By the third wash, the transformation was undeniable. His skin wasn’t flaking, his fur had a matte finish instead of a slick sheen, and he stopped scratching like he was auditioning for a flea circus. Even the vet was impressed. The shampoo didn’t just clean—it recalibrated his skin. The Ophytrium ingredient seems to work like a skin whisperer, calming inflammation and restoring balance without stripping natural oils. I’ve since used it on my other dog, a golden retriever with seasonal dandruff, and it worked just as well. The bottle lasts longer than expected, and the formula rinses clean without leaving residue. It’s become a staple in our grooming routine, and I now recommend it to every pet owner I meet at the dog park.

## Frequently Bought Together

- Douxo S3 SEB Shampoo 16.9 oz (500 mL) - Relief for Seborrhea in Dogs and Cats (Helps with Oily to Flaky Skin)
- Douxo S3 SEB Mousse 5.1 oz (150 mL) - Relief for Seborrhea in Dogs and Cats (Helps with Oily to Flaky Skin)
- Douxo S3 PYO Mousse 5 oz (150 mL)

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---

*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-07-26*