--- product_id: 257288700 title: "Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules" brand: "thorne" price: "R2544" currency: ZAR in_stock: true reviews_count: 5 category: "Thorne" url: https://www.desertcart.co.za/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules store_origin: ZA region: South Africa --- # Boosts brain & nerve function Supports healthy methylation Promotes heart & blood vessel health Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules **Brand:** thorne **Price:** R2544 **Availability:** ✅ In Stock ## Summary > 🛡️ Unlock your body’s genetic potential with every capsule! ## Quick Answers - **What is this?** Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules by thorne - **How much does it cost?** R2544 with free shipping - **Is it available?** Yes, in stock and ready to ship - **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules) ## Best For - thorne enthusiasts ## Why This Product - Trusted thorne brand quality - Free international shipping included - Worldwide delivery with tracking - 15-day hassle-free returns ## Key Features - • **Clean & Pure Formula:** Gluten, dairy, soy, and shellfish free—crafted for mindful, health-conscious professionals. - • **Neuro & Bone Synergy:** Combines B6, B12 & Betaine to enhance brain function, nerve health, and bone strength. - • **Elite Athlete Trusted:** Chosen by 100+ pro sports teams & U.S. National Teams—join the champions’ circle. - • **Holistic Cardiovascular Care:** Clinically trusted formula promoting healthy homocysteine metabolism for heart vitality. - • **Precision Methylation Support:** Active methylated folate (5-MTHF) & B12 for superior absorption and genetic edge. ## Overview THORNE Methyl-Guard delivers 180 capsules of active, methylated folate (5-MTHF), B6, B12 (methylcobalamin), and betaine designed to support healthy methylation, cardiovascular health, brain and nerve function, and bone strength. Trusted by elite athletes and healthcare practitioners alike, this gluten, dairy, soy, and shellfish-free formula is optimized for superior absorption and genetic support, making it a top choice for adults seeking advanced wellness and vitality. ## Description THORNE Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules | Supports Methylation & Healthy Homocysteine Levels for Cardiovascular, Brain & Bone Health, Gluten, Dairy & Soy-Free : desertcart.ae: Automotive Review: Highly recommend. - I am 62 and take 2 vitamins a day per my Dr's instructions. She found that i have the MTHFR deficiency doing a swab test in her office. My body responded really quickly to the vitamin. It has helped me get a lot of water off of my body that i didn't know i was holding. So far 20 pounds of water and that's a lot! I did go through a very short few days where i didn't feel very well but i had read the reviews and instructions and kept taking the vitamins and it past. On the other side of that the energy started to build up. My brain is still 30 but my body isn't 80 any more it's coming down to be of age with energy and ability to accomplish things in a day. I also have a B12 deficiency so i have to take extra B12 because there isn't enough in the vitamin for me but i think because of it I think I'm absorbing it better. I just started my 2nd bottle and have more energy than I've had in 20 years. I never want to run out of this! Highly recommend. Review: Excellent product for MTHFR genetic disorder - Excellent product for MTHFR genetic disorder ## Features - Methylation: Support for healthy methylation - Multiple Functions: Support for heart, blood vessel, brain, nerve, and bone health - Homocysteine: Promotes homocysteine metabolism - Active Bs: Contains the active, methylated forms of folate and vitamin B12 (5-MTHF and methylcobalamin) - Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the 1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey) ## Technical Specifications | Specification | Value | |---------------|-------| | ASIN | B0012FJVA2 | | Age Range Description | Adult | | Allergen Information | Shellfish Free | | Best Sellers Rank | #3,784 in Health ( See Top 100 in Health ) #349 in Multiple Vitamin-Mineral Combination Supplements | | Brand | THORNE | | Brand Name | THORNE | | Color | red | | Container Type | Bottle | | Country of Publication | USA | | Customer Reviews | 4.7 out of 5 stars 2,758 Reviews | | Diet Type | Gluten Free | | Dosage Form | Capsule | | Flavor | Unflavored | | Flavour | Unflavored | | Global Trade Identification Number | 00693749787037 | | Item Dimensions | 7.3 x 7.3 x 13.3 centimeters | | Item Form | Capsule | | Item Weight | 180 Milligrams | | Item form | Capsule | | Item weight | 180 Milligrams | | Manufacturer | Thorne Research | | Manufacturer Part Number | SF787-R | | Material Features | Gluten Free, Soy Free | | Material Type Free | en_AE | | Model Name | SF787 | | Number of Items | 1 | | Primary Supplement Type | Vitamin B and Folate | | Primary supplement type | Vitamin B and Folate | | Product Benefits | Bone & Joint Support, Brain Health Support, Heart Health Support, Nerve Support | | Specific Uses For Product | Heart | | UPC | 693749787037 885335121343 884733360033 885100656025 881619227596 | | Unit Count | 180.0 Count | | Unit count | 180.0 Count | ## Product Details - **Age range (description):** Adult - **Brand:** THORNE - **Diet type:** Gluten Free - **Flavour:** Unflavored - **Item dimensions L x W x H:** 7.3 x 7.3 x 13.3 centimeters - **Item form:** Capsule - **Item weight:** 180 Milligrams - **Primary supplement type:** Vitamin B and Folate - **Product benefits:** Bone Health Support - **Unit count:** 180.0 Count ## Images ![Methyl-Guard, Active Folate, B6, B12 & Betaine, 180 Capsules - Image 1](https://m.media-amazon.com/images/I/61kCTgAaeVL.jpg) ## Available Options This product comes in different **Set** options. ## Questions & Answers **Q: What makes Thorne supplements high quality?** A: Thorne produces high-quality supplements through rigorous testing, well-researched ingredient sourcing, and strict manufacturing standards. We avoid unnecessary additives, binders, and fillers that may interfere with nutrient absorption. **Q: How does Thorne test its supplements for quality?** A: To confirm the purity of our ingredients, the potency of our formulas, and the absence of all contaminants, we carry out a minimum of four rounds of testing on every product we produce. 100+ Thorne employees are dedicated to ensuring quality. **Q: Are Thorne supplements clinically Reviewed and safe?** A: Thorne partners with researchers and conducts clinical trials to support the efficacy of our products. Our team of doctors and medical experts substantiate each ingredient in every formula based on extensive clinical research and medical literature. **Q: Why are Thorne products more expensive than other supplements?** A: When it comes to the health of our customers, we never settle. Thorne products may be priced higher than some others because of our commitment to quality at every step. We don’t simply meet the standard in dietary supplements — we set the standard. **Q: Where are Thorne supplements made and where are the ingredients sourced from?** A: Located in South Carolina, Thorne manufactures supplements in the USA using globally sourced ingredients. When it comes to ingredient sourcing, we seek out only the highest-quality ingredients, selecting each one for its purity and effectiveness. ## Customer Reviews ### ⭐⭐⭐⭐⭐ Highly recommend. *by L***Y on 8 June 2026* I am 62 and take 2 vitamins a day per my Dr's instructions. She found that i have the MTHFR deficiency doing a swab test in her office. My body responded really quickly to the vitamin. It has helped me get a lot of water off of my body that i didn't know i was holding. So far 20 pounds of water and that's a lot! I did go through a very short few days where i didn't feel very well but i had read the reviews and instructions and kept taking the vitamins and it past. On the other side of that the energy started to build up. My brain is still 30 but my body isn't 80 any more it's coming down to be of age with energy and ability to accomplish things in a day. I also have a B12 deficiency so i have to take extra B12 because there isn't enough in the vitamin for me but i think because of it I think I'm absorbing it better. I just started my 2nd bottle and have more energy than I've had in 20 years. I never want to run out of this! Highly recommend. ### ⭐⭐⭐⭐⭐ Excellent product for MTHFR genetic disorder *by C***Y on 11 September 2025* Excellent product for MTHFR genetic disorder ### ⭐⭐⭐⭐⭐ Just what the doctor ordered! *by L***. on 25 February 2025* Recently I found out I’m anemic and distant to go on medication so I did my research and found this to have all the things I need. ## Frequently Bought Together - THORNE Methyl-Guard - Methylation Support Supplement* with Folate and Vitamin B12-180 Capsules - THORNE Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular, and Immune Function* - NSF Certified for Sport - Dairy-Free, Soy-Free - 60 Capsules - THORNE Berberine - Dual Action Formula with Phytosome Plus Botanical Extract - Support Heart Health, Immune System, Healthy GI, Cholesterol* - Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings --- ## Why Shop on Desertcart? - 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016 - 🌍 **Shop Globally** — Access 737+ million products across 21 categories - 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price - 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members) - 🔒 **Secure Payments** — Trusted payment options with buyer protection - ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews **Shop now:** [https://www.desertcart.co.za/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules](https://www.desertcart.co.za/products/257288700-methyl-guard-active-folate-b6-b12-and-betaine-180-capsules) --- *Product available on Desertcart South Africa* *Store origin: ZA* *Last updated: 2026-09-14*