---
product_id: 16372381
title: "Isis Pharma Neotone Pigmentation Spots - Serum"
brand: "isispharma"
price: "R982"
currency: ZAR
in_stock: true
reviews_count: 8
category: "Isis Pharma"
url: https://www.desertcart.co.za/products/16372381-isis-pharma-neotone-pigmentation-spots-serum
store_origin: ZA
region: South Africa
---

# Natural brightening complex Dual exfoliation power Melanin prevention shield Isis Pharma Neotone Pigmentation Spots - Serum

**Brand:** isispharma
**Price:** R982
**Availability:** ✅ In Stock

## Summary

> ✨ Glow Beyond Limits: Unlock radiant, even skin every night! ✨

## Quick Answers

- **What is this?** Isis Pharma Neotone Pigmentation Spots - Serum by isispharma
- **How much does it cost?** R982 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.za](https://www.desertcart.co.za/products/16372381-isis-pharma-neotone-pigmentation-spots-serum)

## Best For

- isispharma enthusiasts

## Why This Product

- Trusted isispharma brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Advanced Brightening Trio:** Licorice, α-Arbutin, and Vitamin C team up to slow melanogenesis by targeting tyrosinase activity, ensuring long-term even skin tone.
- • **Melanin Formation Blocker:** Diacetyl Boldine acts as a potent barrier preventing new pigmentation spots from forming, keeping your complexion flawless.
- • **Powerful Dual-Acid Exfoliation:** Glycolic + Salicylic acids work synergistically to dissolve and remove preformed melanin, revealing brighter skin nightly.
- • **Subtle Aloe Scent & Lightweight Serum:** Enjoy a refreshing aloe aroma with a fast-absorbing formula that layers perfectly under your night care, making every application a treat.
- • **Dermatologist-Tested & Non-Comedogenic:** Clinically proven safe for all skin types, this serum fits seamlessly into your nightly routine without clogging pores.

## Overview

Isis Pharma Neotone Pigmentation Spots Serum is a dermatologist-tested, non-comedogenic formula combining glycolic and salicylic acids for exfoliation, diacetyl boldine to prevent melanin formation, and a potent blend of licorice, α-arbutin, and ascorbic acid to slow melanogenesis. Designed for all skin types, this 30ml serum targets hyperpigmentation effectively with a lightweight, aloe-scented texture ideal for nightly use.

## Description

MAIN INGREDIENTS PROPERTIES DIACETYL BOLDINE: prevents the apparition of melanin LICORICE + α-ARBUTIN + ASCORBIC ACID: slow down the melanogenesis GLYCOLIC ACID + SALICYLIC ACID: exfoliate the preformed melanin HOW TO USE Apply NEOTONE every night on the hyperpigmented areas or as directed by your dermatologist or healthcare professional. Can be used before your daily night care. Avoid any contact with eyes. NON COMEDOGENIC TESTED UNDER DERMATOLOGICAL CONTROL

Review: Constancia para resultos asegurados - En mi caso, logré resultados después de un mes de uso, cambios realmente impresionantes, que complementé con un jabón que cuida y protege la piel, van a recuperar el color natural de esas partes que han tomado otro camino y que pueden llegar a generar inseguridades. En mi caso funciona mejor el gel (Sin color) que el suero (color blanco); es muy importante que se escoja un producto que no afecte la tonalidad de tu piel, sino que la recupere y se adapte a él.
Review: Buen producto - Muy buena me ayuda con las manchas de melasma ayuda aclarar

## Features

- ISIS PHARMA NEOTONE PIGMENTATION SPOTS - SERUM
- GLYCOLIC ACID + SALICYLIC ACID: exfoliate the preformed melanin
- DIACETYL BOLDINE: prevents the apparition of melanin
- LICORICE + α-ARBUTIN + ASCORBIC ACID: slow down the melanogenesis through the attenuation of the tyrosinase’s action

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00CI2KP9O |
| Active Ingredients | ascorbic acid,glycolic acid,licorice,salicylic acid |
| Best Sellers Rank | #114,243 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #2,273 in Facial Serums |
| Brand | IsisPharma |
| Brand Name | IsisPharma |
| Customer Reviews | 4.5 out of 5 stars 725 Reviews |
| Item Form | Serum |
| Item Volume | 30 Milliliters |
| Item Weight | 0.03 Kilograms |
| Manufacturer | Isis Pharma |
| Number of Items | 1 |
| Product Benefits | Exfoliating |
| Recommended Uses For Product | Uneven Pigment |
| Scent | Aloe |
| Scent Name | Aloe |
| Skin Tone | All |
| Skin Type | All |
| Special Ingredients | glycolic_acid, salicylic_acid |
| Target Use Body Part | Face |
| UPC | 639382121180 784190477834 792486553827 |
| Unit Count | 1.02 Fluid Ounces |
| Use for | Face |

## Product Details

- **Product Benefits:** Exfoliating
- **Scent:** Aloe
- **Skin Type:** All
- **Special Ingredients:** glycolic_acid, salicylic_acid
- **Use for:** Face

## Images

![Isis Pharma Neotone Pigmentation Spots - Serum - Image 1](https://m.media-amazon.com/images/I/61EiBUdB2SL.jpg)

## Questions & Answers

**Q: Is that work for dark circles?**
A: Hi
its treat dark-spot  not sure if treat Circels . you visit ISIS pharma company website .there Doctors assigned to give you free consultation online

**Q: CHow to use Neotone serum? Can i apply it on the whole face? or only the hyperpigmented areas?thanks.**
A: I only use on the hyperpigmented area.

**Q: is this good for bikini line darkest and armpits?**
A: not for for bikini line darkest and armpits
use On your face, neckline, and hands
Use Neotone Serum every night on darks spots visible .
During the treatment period, use suitable sun protection : Neotone Radiance SPF 50+ or a product from the Uveblock range with SPF 50+ on areas exposed to the sun.

**Q: What are the Ingredients?**
A: Thanks to its combined formula of 6 synergic active ingredients, NEOTONE stops the overproduction of melanin and eliminates efficiently the pigmentation spots already present in the skin:

1. Glycolic Acid exfoliates gently the preformed melanin from the skin’s surface. It clears the skin exfoliating dead cells

2. Ascorbic Acid enhances skin radiance. Its reveals and renews a luminous skin

3. Salicylic Acid exfoliates through the reduction of corneocyte

4. Alpha-Arbutin which inhibits melanogenesis through tyrosinase inhibition

5. Lumiskin (Diacetyl Boldine) inhibits tyrosinase activity

6. Licorice Extract acts on melanin overproduction and tyrosinase inhibition

## Customer Reviews

### ⭐⭐⭐⭐⭐ Constancia para resultos asegurados
*by C***O on January 25, 2026*

En mi caso, logré resultados después de un mes de uso, cambios realmente impresionantes, que complementé con un jabón que cuida y protege la piel, van a recuperar el color natural de esas partes que han tomado otro camino y que pueden llegar a generar inseguridades. En mi caso funciona mejor el gel (Sin color) que el suero (color blanco); es muy importante que se escoja un producto que no afecte la tonalidad de tu piel, sino que la recupere y se adapte a él.

### ⭐⭐⭐⭐⭐ Buen producto
*by M***S on January 9, 2026*

Muy buena me ayuda con las manchas de melasma ayuda aclarar

### ⭐⭐⭐⭐⭐ Bueno
*by O***H on December 16, 2025*

Es un excelente sérum contra el melasma mejora muchísimo las manchas

## Frequently Bought Together

- Isis Pharma Neotone Pigmentation Spots - Serum
- Isis Pharma Neotone Prevent SPF 50+, 30ml
- ISISPharma NEOTONE LIGHTENING EYE CONTOUR CARE Cream - Gel 15 ml

---

## Why Shop on Desertcart?

- 🛒 **Trusted by 1.3+ Million Shoppers** — Serving international shoppers since 2016
- 🌍 **Shop Globally** — Access 737+ million products across 21 categories
- 💰 **No Hidden Fees** — All customs, duties, and taxes included in the price
- 🔄 **15-Day Free Returns** — Hassle-free returns (30 days for PRO members)
- 🔒 **Secure Payments** — Trusted payment options with buyer protection
- ⭐ **TrustPilot Rated 4.5/5** — Based on 8,000+ happy customer reviews

**Shop now:** [https://www.desertcart.co.za/products/16372381-isis-pharma-neotone-pigmentation-spots-serum](https://www.desertcart.co.za/products/16372381-isis-pharma-neotone-pigmentation-spots-serum)

---

*Product available on Desertcart South Africa*
*Store origin: ZA*
*Last updated: 2026-02-27*